灰阶超声造影对膀胱癌分期诊断的临床价值  

Clinical value of gray-scale contrast-enhanced ultrasound in the staging of bladder cancer

作　　者：陆毅[1] 吴宗林 孙晓岚 吕承勋 王曙 LU Yi;WU Zong-lin;SUN Xiao-lan(Department of Urology,Shidong Hospital Affiliated to Shanghai University of Technology,Shanghai 200438,China)

机构地区：[1]上海理工大学附属市东医院泌尿外科,上海200438

出　　处：《临床和实验医学杂志》2020年第18期2015-2016,F0003,共3页Journal of Clinical and Experimental Medicine

基　　金：上海市卫生和计划生育委员会基金(编号:20164Y0050)。

摘　　要：目的观察灰阶超声造影对膀胱癌分期诊断的临床价值。方法回顾性分析2018年1月至2019年12月上海理工大学附属市东医院收治的68例膀胱癌患者的临床资料,分别采用螺旋CT增强扫描(CT组)与灰阶超声造影(灰阶超声组),将病理学诊断分期作为金标准,比较CT组与灰阶超声组对膀胱癌分期诊断符合率及敏感性、特异性。结果灰阶超声组对T 1~T 4膀胱癌分期诊断符合率分别为94.7%、87.5%、65.2%、80.0%,CT组分别为89.5%、75.0%、78.3%、70.0%,两组T 2、T 3分期差异具有统计学意义(P<0.05);灰阶超声组对T 2期膀胱癌诊断敏感性、特异性、阴性预测值、阳性预测值分别为85%、88%、69%、69%,高于CT组的68%、71%、60%、60%,T 3期分别为65%、73%、71%、81%,低于CT组的88%、90%、88%、88%,差异具有统计学意义(P<0.05)。结论灰阶超声造影应用于膀胱癌分期诊断,操作简单、安全性高,与病理分期符合率高,且在T 2分期诊断中敏感性、特异性优于螺旋CT,可予以推广。Objective To observe the clinical value of gray-scale contrast-enhanced ultrasonography in the staging diagnosis of bladder cancer.Methods The clinical data of 68 patients with bladder cancer admitted to Shidong Hospital Affiliated to Shanghai University of Technology from January 2018 to December 2019 were analyzed retrospectively.Using spiral CT enhanced scan(CT group)and gray-scale contrast-enhanced ultrasound(gray-scale ultrasound group),the pathological diagnosis stage was taken as the gold standard,and the coincidence rate,sensitivity and specificity of CT group and gray-scale ultrasound group in the diagnosis of bladder cancer stage were compared.Results The coincidence rate of staging diagnosis of T 1-T 4 bladder cancer was 94.7%,87.5%,65.2%and 80.0% in gray-scale ultrasound group,and 89.5%,75.0%,78.3%and 70.0% in CT group,respectively.There was significant difference in T 2 and T 3 staging between the two groups(P<0.05);the sensitivity,specificity,negative predictive value and positive predictive value of gray-scale ultrasound group were 85%,88%,69% and 69% respectively,which were higher than those of CT group(68%,71%,60%,60%),and those of T 3 group(65%,73%,71%,81%),which were lower than those of CT group(88%,90%,88%,88%).The difference was statistically significant(P<0.05).Conclusion Gray scale contrast-enhanced ultrasound in the diagnosis of bladder cancer staging,simple operation,high safety,high coincidence rate with pathological staging,and in T2 staging diagnosis sensitivity,specificity is better than spiral CT,can be popularized.

关 键 词：膀胱癌 灰阶超声造影 螺旋CT 分期诊断 敏感性 特异性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.14[医药卫生—诊断学]