正交试验法优选蒙药三臣小儿退热贴的提取工艺  

Optimization of the extraction process of Mongolian Medicine Sanchen Xiaoer Tuiretie by Orthogonal test

作　　者：立新[1] 巴德玛斯仁 云峰 奥·乌力吉[2] Li xin;Badma Siren;Cloud Peak;Ao Uliji(School of Mongolian medicine,Inner Mongolia University for Nationalities,Tongliao 028000;Affiliated Hospital of Mongolian Medicine College,Inner Mongolia University for Nationalities,Tongliao 028000)

机构地区：[1]内蒙古民族大学附属医院,通辽028000 [2]内蒙古民族大学蒙医药学院,通辽028000

出　　处：《北方药学》2020年第8期8-10,共3页Journal of North Pharmacy

基　　金：中央引导地方科技发展专项资金-蒙医药现代化关键技术研究及蒙药产业化蒙药研发国家地方联合工程研究中心能力提升项目-课题(3)蒙药三臣小儿退热贴研制及质量标准药效机制研究内蒙古自治区人民政府蒙医药标准化项目2020-MB018。

摘　　要：目的:优化蒙药三臣小儿退热贴最佳提取工艺条件。方法:以羟基红花色素A提取率和出膏率为指标,正交试验优选最佳提取工艺条件。结果:提取工艺条件为15倍量60%乙醇为溶剂,回流提取3次,每次60min,羟基红花黄色素A提取率达到98.9%;结论:该方法稳定可行。Objective:To select the best extraction process of the effective components of safflower.Method:taking the content of pigment A and extraction rate of hydroxyl safflower as the indexes,the effects of solvent,solvent multiple,extraction time,extraction times and other four factors on the extraction of effective components and content of safflower were selected by orthogonal experiment.Results:reflux extraction was performed 3 times in 15 times of 60%ethanol solution,each time 60 minutes was the best extraction process for the effective components of safflower.Conclusion:the stability and repeatability of this method are suitable for the extraction of effective components of safflower.

关 键 词：蒙药 三臣小儿退热贴 提取工艺 

分 类 号：R29[医药卫生—民族医学]