踩跷法联合中药外敷对腰椎间盘突出症患者症状改善情况及炎症因子和TXB2水平的影响  

Effects of stepping method combined with external application of Chinese Medicine on the improvement of symptoms and levels of inflammatory factors and TXB2 in the patients with lumbar disc herniation

作　　者：叶鑫[1] 吕立江[1] 李增图[1] 李世龙[1] YE Xin;LV Lijiang;LI Zengtu;LI Shilong(Department of Massage,the Third Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou310000,China)

机构地区：[1]浙江中医药大学附属第三医院推拿科,浙江杭州310000

出　　处：《中国现代医生》2020年第22期7-12,共6页China Modern Doctor

基　　金：国家自然科学基金面上项目(81774442);国家临床重点专科(推拿科)建设项目(国卫医发2013-42);浙江省基础公益研究计划项目(LQ18H270005)。

摘　　要：目的分析踩跷法联合中药外敷对腰椎间盘突出症患者症状改善情况,及对患者血液中炎症因子和TXB2水平的影响。方法选择我院2017年1月~2019年6月收治的70例腰椎间盘突出症患者,随机分为观察组和对照组。对照组采用常规方案治疗,观察组在对照组基础上采用踩跷法联合中药外敷方案进行治疗。治疗结束后对患者临床疗效进行评估:评价治疗前后患者腿痛及麻刺、腰痛感、腰椎生理曲度、腰椎JOA症状、疼痛等情况;检查患者全血黏稠(高切)、全血黏稠(低切)、血浆黏度、聚集指数、血沉、肿瘤坏死因子(TNF-α)、白细胞介素1β(IL-1β)及血栓素B2(TXB2)水平。结果观察组患者治疗总有效率(100.00%)明显高于对照组(88.57%),差异有统计学意义(P<0.05);治疗后观察组患者腿痛及麻刺、腰痛评分、腰椎生理曲度、主观症状评分、体征评分、膀胱功能评分、日常生活评分及VAS评分均明显优于对照组,差异有统计学意义(P<0.05);治疗后观察组患者全血黏稠(高切)、全血黏稠(低切)、血浆黏度、聚集指数、血沉、TNF-α、IL-1β、TXB2明显低于对照组,差异有统计学意义(P<0.05)。结论踩跷法联合中药外敷治疗腰椎间盘突出症可显著改善患者症状,并显著降低患者血液中炎症因子和TXB2水平。Objective To analyze the stepping method combined with external application of Chinese medicine in the improvement of symptoms for the patients with lumbar intervertebral disc herniation and its effect on inflammatory factors and TXB2 levels in patients.Methods 70 patients with lumbar disc herniation who were admitted and treated in our hospital from January 2017 to June 2019 were randomly divided into the observation group and the control group;the control group was given conventional regimen for treatment,and the observation group was given stepping method combined with external application of traditional Chinese medicine on the basis of the control group.The clinical efficacy of patients after treatment was evaluated;patients'leg pain and tingling,lumbago,physiological curvature of the lumbar spine,JOA symptoms and pain of the lumbar spine were observed before and after treatment;the whole blood viscosity(high cut),whole blood viscosity(low cut),plasma viscosity,aggregation index,erythrocyte sedimentation rate,tumor necrosis factor(TNF-α),interleukin 1β(IL-1β)and thromboxane B2(TXB2)levels were detected in the patients.Results The total effective rate of treatment in the observation group(100.00%)was significantly higher than that in the control group(88.57%),and the difference was statistically significant(P<0.05);After treatment,the leg pain and tingling,lower back pain score,lumbar spine curvature,subjective symptom score,physical sign score,bladder function score,daily life score and VAS score in the observation group were significantly better than those in the control group,and the differences were statistically significant(P<0.05);after treatment,the whole blood viscosity(high cut),whole blood viscosity(low cut),plasma viscosity,aggregation index,erythrocyte sedimentation rate,TNF-α,IL-1β,and TXB2 in the observation group were significantly lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusion The stepping method combined with external applicatio

关 键 词：踩跷法 中药外敷 腰椎间盘突出症 症状 炎症因子 TXB2 

分 类 号：R681.5[医药卫生—骨科学]