大成汤治疗脊柱胸腰段骨折后腹胀便秘临床观察  

Analysis of the Clinical Effect of Dacheng Decoction on Abdominal Distension and Constipation after Thoracolumbar Fracture

作　　者：王肖虎[1] 杨杰[1] 周亚旗 李智伟[1] 朱智[1] WANG Xiaohu;YANG Jie;ZHOU Yaqi;LI Zhiwei;ZHU Zhi(Zhengzhou Central Hospital Affiliated to Zhengzhou University,Bone I Ward,Zhengzhou 450007,Henan,China)

机构地区：[1]郑州大学附属郑州中心院骨一病区,河南郑州450007

出　　处：《实用中医内科杂志》2020年第8期41-43,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：河南省医学教育研究项目(2017KY043)。

摘　　要：目的探究对脊柱胸腰段骨折后腹胀便秘患者应用大成汤治疗的临床疗效。方法选取2017年3月—2020年3月收治的脊柱胸腰段骨折后腹胀便秘患者120例,均通过CT、核磁共振成像(MRI),结合临床症状确诊,男72例,女48例;平均年龄(52.10±3.69)岁;根据双盲法均分为两组。对照组60例番泻叶50 g,冲服,2次/d,连续治疗3 d。研究组60例大成汤治疗,芒硝、苏木、陈皮、枳实、当归、红花、生大黄、厚朴、地龙、木香,水煎服,每日分早晚2次服用,连续治疗3 d。评价及比较两组疗效、治疗后不同时段的排便情况、不良反应率。结果研究组的总有效率高于对照组,差异有统计学意义(P <0.05);研究组在治疗后1 d、2 d、3 d的排便次数、矢气次数均多于对照组,差异有统计学意义(P <0.05);研究组的不良反应率低于对照组,差异有统计学意义(P <0.05)。结论对脊柱胸腰段骨折后腹胀便秘应用大成汤治疗,疗效更满意,可促使矢气、排便,有效缓解腹胀便秘症状,且不良反应少,提高耐受性以及依从性,是一种安全有效的治疗方法,值得临床广泛应用。Objective To explore the clinical effect of Dachengdecoction in the treatment of abdominal distention and constipation after thoracolumbar fracture. Methods From March 2017 to March 2020,120 patients with abdominal distention and constipation after thoracolumbar fracture in our hospital were selected. All of them were confirmed by CT,MRI and clinical symptoms. 72 were male and 48 were female. The median age was( 52. 10 ± 3. 69) years old. According to double-blind method,they were divided into two groups. The control group( n = 60) received 50 g senna leaf,which was treated by oral administration twice a day for 3 days. The study group( n = 60) was treated with Dacheng decoction,which consisted of mirabilite,Sumu,tangerine peel,Fructus aurantii,angelica,safflower,rhubarb,Magnolia officinalis,earthworm and woodfragrance. The decoction was taken twice a day in the morning and evening,and the treatment lasted for three days. To evaluate and compare the efficacy,defecation and adverse reaction rate of the two groups. Results The total effective rate of the study group was higher than that of the control group,which was statistically significant( P < 0. 05);the defecation times and sagittal gas times of the study group were higher than those of the control group( P < 0. 05),and the adverse reaction rate of the study group was lower than that of the control group,which was statistically significant( P < 0. 05). Conclusion Dacheng decoction is a safe and effective treatment for the patients with abdominal distention and constipation after thoracolumbar fracture,which has more satisfactory effect,can promote sagittal Qi and defecation,effectively relieve the symptoms of abdominal distention and constipation,and has less adverse reactions,and improves the patients’ tolerance and compliance. It is worth clinical application.

关 键 词：脊柱胸腰段骨折 腹胀 便秘 大成汤 番泻叶 排便 矢气次数 不良反应 

分 类 号：R256.35[医药卫生—中医内科学]