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作 者:陈雪 朱海玲[2] 孙合圣 王婷婷 刘晓庆 CHEN Xue;ZHU Hailing;SUN Hesheng;WANG Tingting;LIU Xiaoqing(Department of Pediatrics,Sunshine Union Hospital,Weifang,Shandong 261061,China;Department of Pediatrics,Affiliated Hospital of Weifang Medical College,Weifang,Shandong 261031,China)
机构地区:[1]阳光融和医院儿科,山东潍坊261061 [2]潍坊医学院附属医院儿科,山东潍坊261031
出 处:《重庆医学》2020年第17期2889-2892,共4页Chongqing medicine
基 金:山东省潍坊市卫生和计划生育委员会计划项目(2016wsjs074)。
摘 要:目的探讨3%高渗盐水雾化后拍背吸痰在毛细支气管炎患儿治疗中的临床效果及安全性。方法选择2017年4月至2018年3月就诊于阳光融和医院儿科和潍坊医学院附属医院儿科的2~12月龄毛细支气管炎患儿265例为研究对象,试验过程中脱落3例,按照随机数字表法将患儿分为试验组和对照组,试验组132例,对照组133例。对照组给予包括氧疗、止咳、镇静、抗感染治疗等常规对症治疗。试验组在常规对症治疗基础上给予3%高渗盐水3 mL+肾上腺素1 mL雾化,并在15 min后进行拍背吸痰,3次/天。治疗后评估患儿的呼吸道疾病严重程度评分、肺功能及住院时间,并观察有无不良反应。结果治疗前两组患儿年龄、性别、就诊时间、肺功能、呼吸道疾病严重程度评分差异均无统计学意义(P>0.05)。治疗后试验组患儿呼吸道疾病严重程度评分、肺功能、平均住院时间均优于对照组(P<0.05)。结论3%高渗盐水雾化后拍背吸痰治疗婴幼儿毛细支气管炎疗效显著且安全。Objective To investigate the clinical effect and safety of 3%hypertonic saline atomization and sputum suction in children with bronchiolitis.Methods A total of 265 children with bronchiolitis at 2~12 months old admitted to the department of Pediatrics of Sunshine Union Hospital and Affiliated hospital of Weifang Medical College from April 2017 to March 2018 were selected as research objects.Children were randomly divided into the experimental group(n=132)and the ordinary group(n=133).The ordinary group received routine symptomatic treatment including oxygen therapy,cough relief,sedation and anti-infection treatment.The experimental group was given 3 mL of 3%hypertonic saline and 1 mL of adrenalin atomization on the basis of routine symptomatic treatment,and sputum was sucked after atomization for 3 times per day.The severity score of respiratory disease,pulmonary function,hospitalization time and the adverse reactions were assessed after treatment.Results Before treatment,there were no statistically significant differences in age,gender,time of visit,lung function,and severity score of respiratory disease between the two groups(P>0.05).After treatment,severity score of respiratory disease,lung function and average hospitalization days in the experimental group were better than those in the ordinary group(P<0.05).Conclusion 3%hypertonic saline atomization and sputum suction is effective and safe in the treatment of children′s bronchiolitis.
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