Synthesis and Fungicidal Activity of Chlorothalonil Derivatives  

作　　者：Han Jintao Li Jintao Wang Yingxiu Jiang Aizhong 

机构地区：[1]Shandong Key Laboratory for Chemical Pesticides,Shandong Academy of Pesticide Sciences,Jinan 250100,China

出　　处：《Plant Diseases and Pests》2020年第3期15-17,27,共4页植物病虫害研究（英文版）

基　　金：Supported by Agricultural Science and Technology Innovation Project of Shandong Academy of Agricultural Sciences(CXGC2018E19).

摘　　要：[Objective]The paper was to develop a novel fungicide with high efficacy and low toxicity.[Method]Chlorothalonil was used as the parent structure,and its 4-position substituent was converted to amino group.Totally 12 amide compounds not reported in the literature were designed and synthesized.Their structures were conformed by 1H NMR.[Result]The preliminary bioassay test showed that compounds JTCN-01,JTCN-05 and JTCN-07 had good control effect on corn rust at the concentration of 200 mg/L,and the control effect of compound JTCN-05 reached 95%.[Conclusion]Some chlorothalonil derivatives had the potential for further development.

关 键 词：CHLOROTHALONIL Novel compound SYNTHESIS Fungicidal activity 

分 类 号：TQ455.4[化学工程—农药化工]