Revlites SI激光联合双波长染料激光治疗面部皮肤光老化的疗效观察  

Observation on effect of Revlites SI laser combined with dual-wavelength dye laser in treating facial skin photoaging

作　　者：赵丽靓 张小锋[1] 陈旭东[1] 许清华 户刚[1] 蔡杰 王红[1] 袁晓燕[1] 赵举辉 ZHAO Liliang;ZHANG Xiaofeng;CHEN Xudong;XU Qinghua;HU Gang;CAI Jie;WANG Hong;YUAN Xiaoyan;ZHAO Juhui(Department of Medical Aesthetic Plastic Surgery,Hanzhong Municipal Central Hospital,Hanzhong,Shaanxi 723000,China)

机构地区：[1]陕西省汉中市中心医院医疗美容整形外科,陕西汉中723000

出　　处：《检验医学与临床》2020年第18期2634-2637,共4页Laboratory Medicine and Clinic

基　　金：陕西省汉中市中心医院院级科研基金中标项目(YK1820)。

摘　　要：目的探讨双波长染料激光联合Revlites SI激光治疗面部皮肤光老化的疗效。方法将2018年1月至2019年6月该院收治的60例面部皮肤光老化女性患者纳入研究,按治疗方案不同分成研究组、对照组,各30例。对照组患者单纯接受Revlites SI激光治疗,研究组患者接受双波长染料激光联合Revlites SI激光治疗,每间隔1~2个月接受1次激光治疗,共持续接受治疗8~10次。观察两组患者治疗前后面部皮肤变化、毛细血管扩张改善情况以及并发症发生情况。结果治疗后,两组患者的面部皮肤VISIA评分均显著增高,且研究组高于对照组,差异有统计学意义(P<0.05);研究组患者的毛细血管扩张治疗总有效率为96.67%(29/30),高于对照组的73.33%(22/30),差异有统计学意义(P<0.05)。治疗前,两组患者肤色、细微皱纹及色素沉着评分差异无统计学意义(P>0.05);治疗后,两组患者肤色、细微皱纹及色素沉着评分均显著降低,且研究组低于对照组,差异均有统计学意义(P<0.05)。治疗前,两组患者面部皮损组织氧化应激因子(MDA、LPO、SOD)差异无统计学意义(P>0.05);治疗后,两组患者的MDA、LPO水平降低,SOD水平升高,差异均有统计学意义(P<0.05)。对照组治疗后的并发症总发生率为10.00%(3/30),高于研究组的6.67%(2/30),但差异无统计学意义(P>0.05)。结论双波长染料激光联合Revlites SI激光能缓解或消除皮肤光老化,进一步改善患者面部皮肤状态,疗效确切,并发症少,安全性高。Objective To investigate the efficacy of dual-wavelength dye laser combined with Revlites SI laser in the treatment of facial skin photoaging.Methods Sixty female patients with facial skin photoaging in this hospital from January 2018 to June 2019 were included in this study and divided into the study group and control group according to the different treatment schemes,30 cases in each group.The patients in the control group received the simple Revlites SI laser treatment,and the patients in the study group received the dual-wavelength dye lasers in combination with Revlites SI lasers,once every 1-2 months,for 8-10 consecutive times.The skin changes,telangiectasia improvement and complications occurrence in the two groups were observed before and after treatment.Results After treatment,the facial skin VISIA scores of the two groups were significantly increased,moreover the study group was higher than the control group,and the difference was statistically significant(P<0.05);the total effective rate of telangiectasia in the study group was 96.67%(29/30),which was higher than 73.33%(22/30)in the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in skin color,fine wrinkles and pigmentation scores between the two groups(P>0.05);after treatment,the skin color,fine wrinkles,and pigmentation scores of the two groups were significantly reduced,moreover the study group was lower than the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in oxidative stress factors(MDA,LPO and SOD)in facial skin lesion tissue between the two groups(P>0.05);after treatment,the levels of MDA and LPO in the two groups were decreased,and the level of SOD was increased,and the difference was statistically significant(P<0.05).The occurrence rate of complications after treatment in the control group was 10.00%(3/30),which was higher than 6.67%(2/30)in the study group,but th

关 键 词：双波长染料激光 Revlites SI激光 面部皮肤光老化 毛细血管扩张 

分 类 号：R751.05[医药卫生—皮肤病学与性病学]