电针刺激联合局部振动治疗对脊髓损伤并发下肢痉挛患者康复效果及血清BDNF、PDGF的影响  

Effect of Electroacupuncture Combined with Local Vibration Therapy on Rehabilitation and Serum BDNF and PDGF in Patients with Spinal Cord Injury Complicated with Lower Extremity Spasm

作　　者：黄荷[1] 李翔[1] 韦朝阳 赵春艳[1] 钟格兰[1] 江杨洋 韦梦媛 HUANG He;LI Xiang;WEI Chao-yang;ZHAO Chun-yan;ZHONG Ge-lan;JIANG Yang-yang;WEI Meng-yuan(Department of Rehabilitation Medicine,Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou,Guangxi,545005,China;Department of Rehabilitation Medicine,Guangxi Zhuang Autonomous Region Brain Hospital,Liuzhou,Guangxi,545005,China)

机构地区：[1]广西医科大学第四附属医院康复医学科,广西柳州545005 [2]广西壮族自治区脑科医院康复医学科,广西柳州545005

出　　处：《现代生物医学进展》2020年第15期2948-2951,2956,共5页Progress in Modern Biomedicine

基　　金：广西壮族自治区卫生健康委员会自筹经费科研项目(Z20190574);广西壮族自治区卫生和计划科研项目(Z2016174)。

摘　　要：目的:探讨脊髓损伤(SCI)并发下肢痉挛患者经电针刺激联合局部振动治疗后的临床效果。方法:选取本院于2018年1月到2019年6月期间收治的SCI并发下肢痉挛患者90例,根据乱数表法将上述患者分为对照组(n=45)和研究组(n=45),对照组患者给予常规康复系统疗法治疗,研究组在对照组的基础上给予电针刺激联合局部振动治疗,比较两组患者临床疗效、相关量表评分、内收肌角、直腿抬高角以及血清BDNF、PDGF水平。结果:研究组治疗后的临床总有效率为91.11%(41/45),高于对照组的64.44%(29/45)(P<0.05)。两组患者治疗后改良Barthel指数、血清BDNF、PDGF水平均升高,且研究组高于对照组(P<0.05);改良Ashworth量表、临床痉挛指数评分降低,且研究组低于对照组(P<0.05)。两组患者治疗后内收肌角、直腿抬高角均扩大,且研究组大于对照组(P<0.05)。结论:电针刺激联合局部振动治疗SCI并发下肢痉挛患者,可有效促进患者康复,改善下肢痉挛,提高生活自理能力,同时还可有效改善血清BDNF、PDGF水平。Objective: To explore the clinical effect of electro-acupuncture combined with local vibration therapy in patients with spinal cord injury(SCI) complicated with lower limb spasm. Methods: 90 patients with SCI who were admitted to our hospital from January 2018 to June 2019 were selected, they were divided into control group(n=45) and research group(n=45) according to random number table method. The patients in control group were given routine rehabilitation system therapy. The patients in research group were given electro-acupuncture stimulation combined with local vibration therapy on the basis of the control group. The clinical efficacy,related scale scores, adductor angle, straight leg elevation angle and serum levels of BDNF and PDGF were compared between the two groups. Results: The total effective rate of the research group after treatment was 91.11%(41/45), which was significantly higher than that of the control group 64.44%(29/45)(P<0.05). The modified Barthel, Serum levels of BDNF and PDGF index increased in both groups after treatment, and that in the research group was higher than that in the control group(P<0.05). The scores of modified Ashworth scale and clinical spasm index decreased, and those in the research group were lower than those in the control group(P<0.05). The adductor angle and straight leg elevation angle of both groups were enlarged after treatment, and those in the research group were larger than those in the control group(P<0.05). Conclusion: Electroacupuncture combined with local vibration in the treatment of SCI patients with lower extremity spasm, which can effectively promote the recovery of patients, improve lower extremity spasm, improve the ability of self-care, and also effectively improve the level of serum BDNF and PDGF.

关 键 词：电针 局部振动治疗 脊髓损伤 下肢痉挛 脑源性神经营养因子 血小板衍生生长因子 

分 类 号：R651.2[医药卫生—外科学]