病原微生物感染与自身免疫病  

Microorganism infection and autoimmune diseases

作　　者：刘欣[1] 邓国英[1] 杨淑凤[1] 李星云[1] 戴晓冬(指导)[2] LIU Xin;DENG Guo-Ying;YANG Shu-Feng;LI Xing-Yun;DAI Xiao-Dong(Department of Microbiology,Dalian Medical University,Dalian 116044,China)

机构地区：[1]大连医科大学微生物学教研室,大连116044 [2]大连医科大学寄生虫学教研室,大连116044

出　　处：《中国免疫学杂志》2020年第17期2169-2173,F0004,共6页Chinese Journal of Immunology

摘　　要：自身免疫性疾病(AID)是指由过强自身免疫应答导致的疾病,其发病机制尚未完全阐明。病因学研究认为AID的发病主要源于环境与遗传因素的叠加作用。在环境因素中,微生物感染(细菌、病毒和寄生虫等)与AID发生的相关性备受关注。本文就近年病原微生物感染与AID发病的研究进展进行整理和综述。Autoimmune disease(AID)refers to a disease caused by an over-strong autoimmune response,the pathogenesis of which has not been fully elucidated.Etiological studies believe that pathogenesis of AID is mainly due to the superposition of environmental and genetic factors.Among environmental factors,correlation between microorganism(bacteria,viruses and parasites)and occurrence of AID has attracted much attention.In this paper,the research progress of pathogenic microorganism and occurrence of AID in recent years is collated and reviewed.

关 键 词：自身免疫性疾病 微生物 病毒 

分 类 号：R37[医药卫生—病原生物学]