勃起功能障碍患者肝功能变化及其与IIEF-5、MSF-4评分关系分析  

Changes of liver function indexes and their relationship with IIEF-5,MSF-4 scores in erectile dysfunction patients

作　　者：刘凤霞 阿卜杜热伊木江·如则 刘文娟 杨艳娣 靳瑾 熊鲲 阿地力江·伊明 Feng-xia Liu;Abudureyimujiang·Ruze;Wen-juan Liu;Yan-di Yang;jin Jin;Kun Xiong;Adilijiang·Yiming(Department of Human Anatomy,College of Basic Medicine,Xinjiang Medical University,Urumqi,Xinjiang 830011,China;Department of Human Anatomy and Neurobiology,School of Basic Medical Science,Central South University,Changsha,Hunan 410013,China)

机构地区：[1]新疆医科大学基础医学院人体解剖学教研室,新疆乌鲁木齐830011 [2]中南大学基础医学院人体解剖与神经生物学系,湖南长沙410013

出　　处：《中国现代医学杂志》2020年第17期47-51,共5页China Journal of Modern Medicine

基　　金：新疆“十三五”重点学科(No:2050205);新疆医科大学博士启动基金(No:2019-07)。

摘　　要：目的检测勃起功能障碍(ED)患者肝功能变化并分析其与国际勃起功能指数5项(IIEF-5)和男性性欲量表-4(MSF-4)评分的关系。方法选取2015年5月—2017年12月于新疆医科大学第一、四附属医院男科门诊确诊ED患者100例(ED组)和正常健康者48例(N组)为研究对象。收集IIEF-5、MSF-4评分等资料,采集全血,使用全自动血液分析仪检测肝功能变化,并分析变化的指标与IIEF-5、MSF-4评分的关系。结果ED组IIEF-5和MSF-4评分低于N组(P<0.05)。ED组碱性磷酸酶(ALP)、胆碱酯酶(ChE)高于N组(P<0.05);ED组总蛋白(TP)、总胆红素(TBIL)、总胆汁酸(TBA)低于N组(P<0.05),与IIEF≥12组比较,IIEF<12组ALP、ChE升高,TP、TBIL、TBA降低(P<0.05);与MSF-4≥9组比较,MSF-4<9组ALP、ChE升高,TP、TBILI、TBA降低(P<0.05)。结论肝功能变化可能导致ED患者勃起功能和性欲降低。肝功能指标检测联合IIEF-5、MSF-4评分可较好地为临床ED的诊疗提供参考数据。Objective To study the changes of liver function indexes and their relationship with IIEF-5,MSF-4 scores in erectile dysfunction(ED)patients.Methods We collected 100 cases of ED patients(ED group)and 48 cases normal healthy control(N group)from May 2015 to December 2017 in andrology department in the first and fouth affiliated hospital affiliated to Xinjiang medical university,obtained the related data such as international index of erectile function 5 items(IIEF-5)and male sexual function 4 items(MSF-4)scores and blood,then detected the changes of liver function using automatic blood analyzer,and analyze their relationship with IIEF-5,MSF-4 scores in ED patients.Results Compared with N group,ED group showed lower IIEF-5 and MSF-4 scores;higher ALP,ChE level;lower TP,TBILI,TBA(P<0.05).Increased ALP,ChE and decreased TP,TBILI,TBA were showed in IIEF-5<12,MSF-4<9 groups compared with IIEF-5≥12,MSF-4≥9 groups(P<0.05).Conclusion Changes of liver function may result in significant reductions in erectile function and libido in ED patients.Test of liver function combined with IIEF-5 and MSF-4 scores can provide reference data for clinical diagnosis and treatment of ED.

关 键 词：勃起功能障碍 肝功能 国际勃起功能指数5项 男性性欲量表-4 

分 类 号：R698.1[医药卫生—泌尿科学]