广西大头茶茎化学成分研究  

Chemical Constituents from the Stems of Gordonia kwangsiensis

作　　者：张晓丹 任琦 刘敏 游媛 潘蕾 付辉政 ZHANG Xiao-dan;REN Qi;LIU Min;YOU Yuan;PAN Lei;FU Hui-zheng(Department of Basic Medicine,Jiangxi Health Vocational College,Nanchang 330052,China;Jiangxi Provincial Institute for Drug Inspection and Testing/Jiangxi Provincial Engineering Research Center for Drug and Medical Device Quality,Nanchang 330046,China)

机构地区：[1]江西卫生职业学院基础医学部,江西南昌330052 [2]江西省药品检验检测研究院/江西省药品与医疗器械质量工程技术研究中心,江西南昌330046

出　　处：《中药材》2020年第1期80-83,共4页Journal of Chinese Medicinal Materials

基　　金：国家自然科学基金资助项目(81460589);江西省自然科学青年基金(20142BAB215062)。

摘　　要：目的:研究广西大头茶茎的化学成分。方法:采用正相硅胶、MHPLC、分析型和制备型HPLC等色谱技术对广西大头茶茎的95%乙醇提取物进行分离、纯化,综合运用MS、1H-NMR和13C-NMR等波谱数据鉴定所得化合物结构。结果:从广西大头茶茎中分离纯化得到了9个化合物,分别鉴定为:gordonoside I(1)、gordonoside J(2)、kaempferol-4′-O-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside(3)、芹菜素-7-O-β-D-葡萄糖苷(4)、2α,3α,19α-三羟基乌苏烷-12-烯-28-O-β-D-吡喃葡萄糖苷(5)、2α,3β,19α-三羟基齐墩果-12-烯-23,28-二羧酸(6)、β-胡萝卜苷(7)、白桦酸(8)、齐墩果酸(9)。结论:所有化合物均为首次从该植物中分离得到。Objective:To study the chemical constituents from the stems of Gordonia kwangsiensis.Methods:The chemical constituents of 95%ethanol extract from the stems of Gordonia kwangsiensis were isolated and purified by various column chromatographic techniques,including silica gel,MHPLC,RP-HPLC and p-HPLC.Their structures were identified by MS,1H-NMR,13C-NMR and other spectroscopic analysis.Results:Nine compounds were isolated and purified from the stems of Gordonia kwangsiensis and identified as gordonoside I(1),gordonoside J(2),kaempferol-4′-O-α-L-rhamnopyranosyl(1→6)-β-D-glucopyranoside(3),apigenin-7-O-β-D-glucoside(4),2α,3α,19α-trihydroxyurs-12-en-28-O-β-D-glucopyranoside(5),2α,3β,19α-trihydroxyolean-12-en-23,28-dioic acid(6),β-daucosterol(7),betulinic acid(8),oleanolic acid(9),respectively.Conclusion:All compounds are isolated from this plant for the first time.

关 键 词：广西大头茶茎 大头茶属 化学成分 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]