地枫皮正丁醇部位的化学成分研究  

Chemical Constituents from n-Butanol Extract of Illicium difengpi

作　　者：宁德生[1] 符毓夏 李连春 潘争红[1] 李根 NING De-sheng;FU Yu-xia;LI Lian-chun;PAN Zheng-hong;LI Gen(Guangxi Institute of Botany,Guangxi Zhuang Autonomous Region,Chinese Academy of Sciences/Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization,Guilin 541006,China;College of Chemistry and Bioengineering,Guilin University of Technology,Guilin 541006,China)

机构地区：[1]广西壮族自治区中国科学院广西植物研究所/广西植物功能物质研究与利用重点实验室,广西桂林541006 [2]桂林理工大学化学与生物工程学院,广西桂林541006

出　　处：《中药材》2020年第1期84-87,共4页Journal of Chinese Medicinal Materials

基　　金：广西科技重大专项资助项目(桂科AA18118018-4);广西自然科学基金面上项目(2018GXNSFAA281172);广西植物研究所基本业务费项目(桂植业15003)。

摘　　要：目的:研究地枫皮正丁醇部位的化学成分。方法:利用柱色谱和半制备高效液相色谱分离技术对地枫皮正丁醇部位进行分离纯化,并通过化合物的理化性质和一维核磁共振波谱数据进行化合物结构鉴定。结果:从地枫皮的正丁醇部位中分离得到12个化合物,分别鉴定为:2-allyl-4,5-methylenedioxyphenol-1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside(1)、1-o-[4-hydroxybenzoyl-(6)-β-D-glucopyranoside]-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-3-propanol(2)、michehedyoside F(3)、eugenylβ-rutinoside(4)、2,6-dimethoxy-4-(prop-2-enyl)phenyl O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(5)、trans-isoeugenylβ-rutinoside(6)、cis-isoeugenylβ-rutinoside(7)、原儿茶酸(8)、原花青素B2(9)、儿茶素(10)、芦丁(11)、槲皮苷(12)。结论:其中,化合物4~7、10为首次从该植物中分离得到。Objective:To study the chemical constituents from n-butanol extract of Illicium difengpi.Methods:The compounds from n-butanol extract of Illicium difengpi were isolated and purified through chromatographic separative techniques,including column chromatography and semi-preparative HPLC,the chemical structures were identified by means of physicochemical properties and 1-D NMR data.Results:Twelve compounds were isolated from the n-butanol extract of Illicium difengpi and identified as 2-allyl-4,5-methylenedioxyphenol-1-O-α-L-rhamnopyranosyl-(1→6)-O-β-D-glucopyranoside(1),1-o-[4-hydroxybenzoyl-(6)-β-D-glucopyranoside]-2-[4-(3-hydroxypropyl)-2-methoxyphenoxy]-3-propanol(2),michehedyoside F(3),eugenylβ-rutinoside(4),2,6-dimethoxy-4-(prop-2-enyl)phenyl O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(5),trans-isoeugenylβ-rutinoside(6),cis-isoeugenylβ-rutinoside(7),protocatechuic acid(8),procyanidin B2(9),catechin(10),rutin(11),quercitrin(12),respectively.Conclusion:Compounds 4 to 7,10 are isolated from this plant for the first time.

关 键 词：地枫皮 化学成分 苯丙素苷 黄酮 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]