抗VEGF药物在眼科学与肿瘤学的应用研究进展  

Research progress of anti-neovascularization drugs in the relationship between ophthalmology and oncology

作　　者：章爽 邵毅[1] 高桂平[1] Shuang Zhang;Yi Shao;Gui-Ping Gao(Department of Ophthalmology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China,)

机构地区：[1]南昌大学第一附属医院眼科,中国江西省南昌市330006

出　　处：《国际眼科杂志》2020年第10期1760-1763,共4页International Eye Science

基　　金：江西省自然科学基金资助项目(No.20181BAB205034);江西省教育厅科学技术研究项目(No.GJJ170048)。

摘　　要：新生血管的形成是很多重要眼部疾病的共同病理改变,也是肿瘤生长、转移的基础。本文旨在介绍抗血管内皮生长因子(VEGF)药物在眼科学及肿瘤学领域的联系、应用及相关研究,提出了新的给药途径及目前面临的问题及挑战,以及抗VEGF药物在眼科应用中出现的益处与副作用,强调应该加强眼科医师与肿瘤科医师在基础、临床等方面的密切交流与合作。The formation of neovascularization is not only the common pathological change of many important eye diseases,but also the basis of tumor growth and metastasis.this article introduced the relationship,application and related research of anti-angiogenic drugs in the field of ophthalmology and oncology,it also introduced the new ways of administration,facing problems and challenges now,as well as the benefits and side effects of neovascularization drugs in ophthalmology application.Through the discussion of this article,we should strengthen the communication and cooperation between ophthalmologists and oncologists in basic and clinical aspects.

关 键 词：血管内皮生长因子 抑制剂 新生血管性眼病 肿瘤学 给药途径 

分 类 号：R969[医药卫生—药理学]