影响冠状动脉旁路移植术后静脉桥再狭窄的因素及防治进展  

Influencing factor and prevention of vein graft restenosis after coronary artery bypass grafting

作　　者：倪亦琨 张岩[1] NI Yi-kun;ZHANG Yan(Department of Cardiac Surgery,State Key Laboratory of Cardiovascular Diseasey Fuwai Hospital,National Center for Cardiovascular Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100037,China)

机构地区：[1]中国医学科学院北京协和医学院国家心血管病中心心血管病国家重点实验室阜外医院成人外科中心,北京市100037

出　　处：《中国心血管病研究》2020年第9期840-844,共5页Chinese Journal of Cardiovascular Research

基　　金：北京协和医学院教育教学改革项目(10023201900202)。

摘　　要：冠状动脉旁路移植术(CABG)是治疗冠心病最主要的外科治疗手段,自体大隐静脉是CABG中最常使用的桥血管,但其远期再狭窄率高,严重影响了静脉桥的使用寿命.本文将从手术损伤、血流动力学改变、氧分压变化、静脉本身特点等因素出发探讨静脉桥再狭窄机制,并对其防治进展作一简要综述.Coronary artery bypass grafting(CABG)is the main surgical treatment for coronary atherosclerotic heart disease.The autologous saphenous veins are the most commonly used conduits for surgical revascularization.However,they are associated with a high failure rate.In this review.the pathophysiology underlying vein graft restenosis from the perspective of surgical injury,hemodynamics,partial oxygen pressure and venous characteristics and the progress in prevention and treatment of this disease are explained.

关 键 词：冠状动脉旁路移植术 静脉移植 通畅率 再狭窄 

分 类 号：R654.2[医药卫生—外科学]