TQA数据趋势与TomoTherapy输出稳定性的联系  

Correlation between TQA data trends and output of helical tomotherapy

作　　者：陈济鸿[1] 张秀春[1] 柏朋刚[1] 陆军[1] 陈文娟[1] 陈开强[1] 李奇欣[1] 胡彩容[1] 林金勇[1] CHEN Jihong;ZHANG Xiuchun;BAI Penggang;LU Jun;CHEN Wenjuan;CHEN Kaiqiang;LI Qixin;HU Cairong;LIN Jinyong(Department of Radiation Oncology,Fujian Cancer Hospital/Fujian Medical University Cancer Hospital,Fuzhou 350014,China)

机构地区：[1]福建省肿瘤医院/福建医科大学附属肿瘤医院放疗科,福建福州350014

出　　处：《中国医学物理学杂志》2020年第9期1120-1123,共4页Chinese Journal of Medical Physics

基　　金：福建省卫生健康科技项目(2017-ZQN-15,2018-ZQN-19,2017-CX-8)。

摘　　要：目的:探讨TomoTherapy QualityAssurance(TQA)数据趋势与螺旋断层放疗(Helical Tomotherapy,HT)系统输出的联系。方法:回顾性分析了本院HT系统近3年内TQA各个模块的参数和数据趋势,探讨其与HT系统的静态输出剂量和输出能量(D20/D10)变化的相关性。结果:楔形阶梯静态模块的z轴偏移参数与HT的静态输出剂量的相关性最强(r=0.883,P<0.01)。基本剂量测定模块的出口检测器平整度值对能量变化最敏感(r=0.902),其次是楔形阶梯静态模块的能量差异(r=0.897)和楔形阶梯螺旋模块的能量差异(r=0.852),灵敏度分别为2.3×10^-4、3.1×10^-4和5.7×10^-4。结论:TQA有助于用户追踪HT输出剂量和能量变化,及早进行必要的机器维护或剂量校准。Objective To discuss the relationship between tomotherapy quality assurance(TQA)data trends and output of helical tomotherapy(HT).Methods The correlations between static output and output energy variation(D20/D10)were determined based on the retrospective analysis on the parameters and data trends of each module of TQA of HT in recent 3 years.Results The offset parameter of z axis in step-wedge static module had the best correlation with the static output of HT(r=0.883,P<0.01).The exit detector flatness in basic dosimetry module was the most sensitive to energy changes(r=0.902),followed by energy differences in step-wedge static module(r=0.897)and energy differences in step-wedge helical module(r=0.852),and their sensitivities were 2.3×10^-4,3.1×10^-4 and 5.7×10^-4,respectively.Conclusion TQA can help user to monitor the changes in the output and energy of HT,thereby carrying out necessary maintenance and dosimetric validation earlier.

关 键 词：螺旋断层放疗 TQA 静态输出剂量 射线质 

分 类 号：R318[医药卫生—生物医学工程] R811.1[医药卫生—基础医学]