心室辅助装置血泵内血栓控制研究进展  

Research progress of preventing thrombosis in blood pump of ventricular assist devices

作　　者：龙东平 薛建荣[2] 云忠[3] LONG Dongping;XUE Jianrong;YUN Zhong(Intelligent Manufacturing Institute of Hunan University of Science and Technology,Xiangtan,411201,Hunan,P.R.China;School of Chemistry and Chemical Engineering,Hunan University of Science and Technology,Xiangtan,411201,Hunan,P.R.China;College of Mechanical and Electrical Engineering,Central South University,Changsha,411083,P.R.China)

机构地区：[1]湖南科技大学智能制造研究院,湖南湘潭411201 [2]湖南科技大学化学化工学院,湖南湘潭411201 [3]中南大学机电工程学院,长沙411083

出　　处：《中国胸心血管外科临床杂志》2020年第10期1235-1241,共7页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

基　　金：国家自然科学基金项目(31670999);湖南省教育厅基金项目(15C0544)。

摘　　要：血泵是人工心室辅助装置的关键部件,血栓是血泵使用过程中最严重的并发症之一。可通过对血泵材料进行表面改性,对血泵结构和工作参数进行优化等方法减少和控制血栓。本文对不同类型血泵出现血栓的典型症状及其危害、血栓形成机理和影响血泵内血栓形成的主要因素,以及血栓仿真预测模型等进行综述。Blood pump is the core component of artificial ventricular assist device,and thrombosis is a severe complication of blood pump in clinical application.Methods of controlling and reducing thrombosis include materials surface modification,structure and parameters optimization of blood pump,and others.The typical symptoms of thrombosis and the hazard of various types of blood pump,the formation mechanism and primary factors for thrombosis,and the simulation prediction models for thrombosis were reviewed in this paper.

关 键 词：血泵 血液相容性 血栓 抗凝 综述 

分 类 号：R541.6[医药卫生—心血管疾病]