剪切波速度及其比值对乳腺良恶性结节的鉴别诊断  

Value of shear wave velocity and its ratio in differentiating benign and malignant breast nodules

作　　者：赵颖燕[1] 奚佳颖[1] 金修才[1] ZHAO Yingyan;XI Jiaying;JIN Xiucai(Department of Ultrasound,Changhai Hospital Affiliated to the Second Military Medical University,Shanghai 200433,China)

机构地区：[1]第二军医大学附属长海医院超声科,上海市200433

出　　处：《临床超声医学杂志》2020年第9期703-705,共3页Journal of Clinical Ultrasound in Medicine

摘　　要：目的应用声触诊组织量化成像(VTIQ)技术测量剪切波速度及其比值,探讨其对乳腺良恶性结节的鉴别诊断价值。方法选取经手术病理证实的46例乳腺良恶性结节患者(共46个结节),恶性18个,良性28个,VTIQ测量结节及周围乳腺腺体组织的剪切波速度(SWV),获得良恶性结节SWV平均值及结节与周围乳腺腺体组织SWV平均值的比值;绘制受试者工作特征(ROC)曲线,计算曲线下面积,分析VTIQ对乳腺恶性结节的鉴别诊断价值。结果良恶性结节的SWV值分别为(4.05±0.89)m/s和(6.49±1.88)m/s,差异有统计学意义(P<0.05);良恶性结节与周围乳腺腺体组织SWV值的比值分别为1.26±0.38和2.21±0.86,差异有统计学意义(P<0.05)。以SWV值4.52 m/s为截断值,其诊断恶性病灶的敏感性88.89%,特异性82.14%,准确率84.80%,AUC为0.875;以结节与周围乳腺腺体组织SWV值的比值1.25为截断值,其鉴别诊断恶性结节的敏感性94.44%,特异性78.57%,准确率84.80%,AUC为0.902。结论乳腺结节的SWV值及其与周围乳腺腺体组织SWV值的比值对良恶性结节均有一定鉴别诊断价值,但SWV比值的诊断敏感性更高,可为临床诊断提供依据。Objective To measure the shear wave velocity and its ratio by virtual touch tissue imaging quantification(VTIQ),and to explore the value for differentiating benign and malignant breast nodules.Methods Forty-six patients(46 nodules)confirmed by surgery and pathology were retrospectively analyzed,18 nodules were malignant and 28 nodules were benign.The SWV of benign and malignant nodules and the surrounding tissues were measured.The mean SWV of the nodules and the mean SWV between the nodules and the surrounding breast gland tissues were calculated.The receiver operating characteristic(ROC)curve was drawn,and the area under the curve was calculated to assess the value of VTIQ in differentiating benign and malignant nodules.Results The SWV of benign and malignant nodules were(4.05±0.89)m/s and(6.49±1.88)m/s,respectively,and the difference was statistically significant(P<0.05).The ratio of SWV between benign and malignant lesions and surrounding breast gland tissue were 1.26±0.38 and 2.21±0.86,respectively,and the difference was statistically significant(P<0.05).Taken the SWV of breast nodules was 4.52 m/s,the sensitivity,specificity,accuracy and AUC in the differential diagnosis of malignant nodules were 88.89%,82.14%,84.80%and 0.875,respectively.Taken the ratio of SWV between nodules and surrounding breast gland tissue was 1.25,the sensitivity,specificity,accuracy and AUC in the differential diagnosis of malignant nodules were 94.44%,78.57%,84.80%and 0.902,respectively.Conclusion The SWV of breast nodules and the ratio of SWV between nodules and surrounding breast gland tissues have a certain value in the differential diagnosis of benign and malignant nodules,but the sensitivity of SWV ratio is higher,which can provide reference for clinical diagnosis.

关 键 词：声触诊组织量化成像 剪切波速度 速度比值 乳腺结节 良恶性 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]