CM‑Phos配体在钯催化交叉偶联反应中的应用  

Application of CM-Phos Ligand in Palladium-catalyzed Cross-coupling Reactions

作　　者：苏秋铭 原安莹 邝福儿 陈志强 白呈超 辛伟贤 SO Chauming;YUEN Onying;KWONG Fukyee;CHEN Chihchiang;PAI Chengchao;SUN Raymond Waiyin(Department of Applied Biology and Chemical Technology,the Hong Kong Polytechnic University,Hong Kong,China;Department of Chemistry,the Chinese University of Hong Kong,Hong Kong,China;Guangzhou Lee&Man Technology Company Limited,Guangzhou 510000,China)

机构地区：[1]香港理工大学应用生物及化学科技学系,香港 [2]香港中文大学化学系,香港 [3]广州理文科技有限公司,广州510000

出　　处：《高等学校化学学报》2020年第10期2185-2198,M0002,共15页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:21972122);深圳市基础研究计划项目(批准号:JCYJ20180306173843318)资助.

摘　　要：本文综合评述了近年来2-[2-(二环己膦基)苯基]-1-甲基-1H-吲哚(CM-Phos)膦配体及其衍生物在钯催化的交叉偶联反应中的应用,主要根据不同种类的交叉偶联反应进行系统性分述,并对该领域的发展前景进行了展望.Palladium-catalyzed cross-coupling is one of the most effective and widely utilized tools for con⁃necting electrophilic and nucleophilic coupling partners for carbon-carbon or carbon-heteroatom bonds forming reactions.2-[2-(dicyclohexylphosphino)phenyl]-N-methylindole(CM-Phos)ligand derivatives have proven to be successful catalysts in this context.This review summarizes the recent developments,and applications of different coupling partners in these reactions by using CM-Phos ligand derivatives.

关 键 词：膦配体 2-[2-(二环己膦基)苯基]-1-甲基-1H-吲哚 钯催化 交叉偶联 

分 类 号：O643.3[理学—物理化学]