初探AECOPD患者MSCT容积成像指标与肺功能相关参数间的相关性  

Correlation Between Index of Volume Rendering in MSCT and Parameters Related to Pulmonary Function in Patients with AECOPD

作　　者：苏勇[1] 王蕾[1] 魏卿[1] SU Yong;WANG Lei;WEI Qing(Department of Critical Care Medicine,Pengzhou People's Hospital,Pengzhou 611930,Sichuan Province,China)

机构地区：[1]彭州市人民医院重症医学科,四川彭州611930

出　　处：《中国CT和MRI杂志》2020年第11期73-76,共4页Chinese Journal of CT and MRI

基　　金：四川省科技计划项目(编号:2015FZ0276)。

摘　　要：目的探讨慢性阻塞性肺疾病急性加重期(AECOPD)患者多层螺旋CT(MSCT)容积成像指标与肺功能相关参数间的相关性。方法选取我院2016年9月至2018年3月收治的AECOPD患者52例、正常健康者52例,两组均进行MSCT容积成像与肺功能检查,比较两组相关参数并分析其相关性。结果观察组患者FEV1、FEV1pred、FVC、FEV1/FVC指标水平明显低于对照组,(P<0.001);观察组患者RV、TLC、RV/TLC指标水平显著高于对照组(P<0.001);观察组患者Vin、Vex、Vex/Vin指标水平明显高于对照组(P<0.001);观察组患者Vin-Vex、Vin-Vex/Vin指标水平显著低于对照组(P<0.001);Spearman相关性分析结果显示:FEV1与Vex、Vex/Vin存在负相关性,与Vin-Vex/Vin存在正相关性(P<0.001);FEV1/FVC与Vin、Vex存在负相关性,与Vin-Vex/Vi存在正相关性(P<0.001);RV与Vex、Vex/Vin、Vin-Vex/Vi存在正相关性(P<0.001);TLC与Vex、Vex/Vin存在负相关性,与Vin-Vex/Vi存在正相关性(P<0.001);RV/TLC与Vex、Vex/Vin存在负相关性,与Vin-Vex/Vi存在正相关性(P<0.001)。结论AECOPD患者MSCT容积成像指标与肺功能相关参数间存在一定相关性,根据MSCT容积成像指标水平可评估患者肺功能。Objective To investigate the correlation between index of volume rendering in multi-slice spiral CT(MSCT)and parameters related to pulmonary function in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods A total of 52 AECOPD patients and 52 healthy subjects were enrolled in our hospital from September 2016 to March 2018.Both groups underwent volume rendering of MSCT and examination of pulmonary function.The relevant parameters of two groups were compared and their correlations were analyzed.Results The levels of FEV1,FEV1pred,FVC and FEV1/FVC in the observation group were significantly lower than those in the control group(P<0.001).The levels of RV,TLC and RV/TLC in the observation group were significantly higher than those in the control group(P<0.001).The levels of Vin,Vex and Vex/Vin in the observation group were significantly higher than those in the control group(P<0.001).The levels of Vin-Vex and Vin-Vex/Vin in the observation group were significantly lower than those in the control group(P<0.001).Spearman correlation analysis showed that FEV1 was negatively correlated with Vex and Vex/Vin,and positively correlated with Vin-Vex/Vin(P<0.001);FEV1/FVC was negatively correlated with Vin and Vex,and positively correlated with Vin-Vex/Vi(P<0.001);RV was positively correlated with Vex,Vex/Vin,and Vin-Vex/Vi(P<0.001);TLC was negatively correlated with Vex and Vex/Vin,and positively correlated with Vin-Vex/Vi(P<0.001);RV/TLC was negatively correlated with Vex and Vex/Vin and positively correlated with Vin-Vex/Vi(P<0.001).Conclusion There is a correlation between the index of volume rendering in multi-slice spiral CT(MSCT)and parameters related to pulmonary function in patients with AECOPD.The lung function of patients can be assessed according to the level of index of volume rendering in MSCT.

关 键 词：慢性阻塞性肺疾病急性加重期 计算机断层X线成像 容积成像指标 肺功能 相关性 

分 类 号：R562[医药卫生—呼吸系统]