基于CiteSpace的国内外儿科用药文献研究分析  

Research on Domestic and International Literature of Pediatric Drug Based on CiteSpace

作　　者：李隆杰 王玥 杨林慧 黄锐[1] 曹燕[1] 陈芬 LI Longjie;WANG Yue;YANG Linhui;HUANG Rui;CAO Yan;CHEN Fen(School of Pharmacy,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Department of Statistical,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院药学院,武汉430030 [2]华中科技大学同济医学院附属同济医院统计科,武汉430030 [3]华中科技大学同济医学院附属协和医院,武汉430022

出　　处：《医药导报》2020年第10期1356-1361,共6页Herald of Medicine

基　　金：国家自然科学基金资助项目(71874062);湖北省卫生健康科研基金资助(WJ2019M117)。

摘　　要：目的分别对国内外关于儿科用药的文献进行分析,将国内外儿科用药研究进行对比和总结,以期为我国儿科用药研究提供参考。方法分别以“Pediatric Drug”“儿科用药”为主题词,检索Web of Science核心合集和中国知网(CNKI),将检索得到文献记录导入CiteSpace软件,并从关键词共现分析、被引分析、热点变迁三个方面分析2009—2019年国内外儿科用药文献研究的前沿热点与研究趋势。结果共分析中文文献2200篇,外文文献2509篇。关键词共现分析表明中文文献出现频率最高的关键词是:儿童用药、合理用药、安全用药等,外文文献出现频率最高的是:children、diagnosis、safety等。被引分析发现被引数较多的中文文献大部分为医院门诊的超说明书用药情况调查,而外文文献除对门诊用药情况的调查外更多着眼于药物开发相关的研究。热点变迁分析则显示出中外文文献儿科用药的相关临床研究均增多。结论国内对儿科用药的研究集中在临床用药情况分析,儿科用药开发的相关研究较少,国家应鼓励儿童专用剂型、规格等药物研发工作的开展,完善儿童临床用药规范,加强儿童用药管理。Objective To explore the possible deficiencies in pediatric drug research and provide reference for the drug use in pediatric,by analyzing the literature on pediatric drug use at domestic and international.Methods“Pediatric Drug”was used as the English subject word,and“Pediatric Drugs”was used as the Chinese subject word.The Web of Science core collection database and CNKI were searched respectively.From the three aspects of key words co-occurrence analysis,cited analysis and hotspot change analysis,CiteSpace software is used to analyze the hotspots and trends of pediatric drug literature research at home and abroad from 2009 to 2019.Results A total of 2200 Chinese literature and 2509 English papers were analyzed.Key words co-occurrence analysis showed that the most frequent keywords in Chinese literature were children's drug,rational drug and safe drug.The highest frequent keywords of English literature were children,diagnosis and safety.The cited analysis found that most of the high quoted Chinese literature was about off-label drug use in clinic department,while the English literature focused more on drug development than the investigation of outpatients.The analysis of hotspot changes showed that the clinical research on pediatric drugs in Chinese and English literature increased.Conclusion Compared to drug design,domestic research on pediatric drug use focoues on the analysis of clinical drug use.The state should encourage the research and development of special dosage forms for children's drugs,improve the standards of children's clinical drug use and management is strengthen.

关 键 词：儿科用药 CiteSpace软件 共现分析 被引 聚类 

分 类 号：R954[医药卫生—药学]