基于老年围手术期高风险用药目录的老年手术患者用药情况分析  

High-risk Medications in Elderly Patients in Our Hospital Based on List of High-risk Perioperative Medications

作　　者：董娜 何丹 吴晓燕[1] 张海霞[1] DONG Na;HE Dan;WU Xiaoyan;ZHANG Haixia(Department of Pharmacy,Nanjing Drum Tower Hospital Affiliated to Medical School,Nanjing University,Nanjing Jiangsu 210008,China;School of Basic Medicine and Clinical Pharmacy,China Pharmaceutical University,Nanjing Jiangsu 210008,China)

机构地区：[1]南京大学医学院附属鼓楼医院药学部,江苏南京210008 [2]中国药科大学基础医学与临床药学学院,江苏南京210008

出　　处：《中国药物警戒》2020年第10期692-696,共5页Chinese Journal of Pharmacovigilance

基　　金：南京市科技发展计划项目(201503020);南京大学医学管理研究所课题(NDYG2015005);江苏省药学会-奥赛康临床药学基金科研项目(A201705)。

摘　　要：目的基于老年人围手术期高风险用药目录分析医院老年患者高风险用药情况,为围手术期老年患者的合理用药提供参考。方法采用系统抽样法,随机抽取某三级甲等医院围手术期老年患者230例,以2019年新发布的老年人围手术期高风险用药目录为评价标准,总结分析医院2018年1月至12月高风险用药的情况。结果 230例患者中,涉及279例次用药,36.52%(84/230)的患者围术期使用了高风险药物,29.13%(67/230)的患者使用了2种及以上的高风险药物;共检出11大类37种药物,其中右美托咪定、地西泮、非甾体抗炎药(NSAIDs)使用率较高,分别占总检出药物例次的20.43%、14.35%、11.30%。共有3例患者出现围手术期用药后的不良反应。结论该院围手术期老年患者存在潜在的用药风险,应加强老年患者围手术期用药监管,提高用药质量。Objective To evaluate high-risk medications in elderly patients in our hospital based on the list of high-risk perioperative medications in order to provide more evidence for rational medications in perioperative elderly patients.Methods A total of 230 elderly patients during the perioperative period were selected from January 2018 to December 2018.The list of high-risk perioperative medications for the elderly released in 2019 was used as the criteria to evaluate the high-risk medications detected.Results In the 230 patients,279 medications were detected,36.52%(84/230)of whom received high-risk medications during the perioperative period,and 29.13%(67/230)used two or more types of high-risk drugs.A total of 37 types of drugs were detected,among which dexmedetomidine,diazepam and NSAID were more frequently used,accounting for 20.43%,14.35%and 11.30%respectively.A total of 3 patients developed adverse reactions after perioperative administration.Conclusion There are potential drug risks to perioperative elderly patients in our hospital,so we should strengthen the regulation of perioperative medications in elderly patients and improve the quality of medications.

关 键 词：围手术期 高风险用药目录 老年手术患者 

分 类 号：R969.3[医药卫生—药理学]