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作 者:刘剑[1] 李永辉 路明 张媛[1] LIU Jian;LI Yonghui;LU Ming;ZHANG Yuan(Department of Pharmacy,the Second Hospital of Hebei Medical University,Shijiazhuang Heibei 050000,China;Hebei Drug Monitoring and Evaluation Center,Shijiazhuang Heibei 050000,China)
机构地区:[1]河北医科大学第二医院药学部,河北石家庄050000 [2]河北省药品监测评价中心,河北石家庄050000
出 处:《中国药物警戒》2020年第10期735-739,744,共6页Chinese Journal of Pharmacovigilance
摘 要:目的对医院静脉用药集中调配中心(PIVAS)审核干预的不合理医嘱进行统计分析,为临床用药的合理性、安全性和有效性提供有效参考。方法将2017~2018年医院静脉用药集中调配中心667 705组医嘱数据进行统计,对其中不合理医嘱进行归纳、整理和分析。结果不合理医嘱共16 180组,占总医嘱的2.42%。主要为医嘱开具错误、溶媒品种选择不当、药品使用剂量不当、全胃肠外营养配方问题、溶媒用量不当、药物不宜配伍、药品使用频次不当、成分配伍禁忌、重复用药、药品使用途径不当。结论 PIVAS审方药师通过审核医嘱,能及时介入不合理医嘱并进行干预,降低临床静脉给药不良反应的发生率,保证患者用药合理性和安全性。Objective To statistically analyze the improper prescriptions detected by the pharmacy intravenous admixture service of the Second Hospital of Hebei Medical University between 2017 and 2018 so as to provide reference for the rationality,safety and effectiveness of clinical medication.Methods The data on 667705 medical prescriptions were classified and collected from the pharmacy intravenous admixture service of The Second Hospital of Hebei Medical University from 2017 to 2018.To sum up,sort out and analyze the irrational medical advice.Results There were 16180 irrational medical advices,accounting for 2.42%of the total medical advices.The irrational factors included wrong Format of Doctor's Order,improper selection of solvent varieties,inappropriate dosage of drugs,TPN inappropriate formula,improper dosage of solvent,nappropriate compatibility of drugs,improper frequency of drug use,incompatibility of drugs in a prescription,repeated medication,incorrect use of drugs.Conclusion Irrational medical prescriptions can be found and intervened in time by examination of prescriptions of pharmacists,which not only can reduce the incidence of intravenous administration clinical adverse reactions,but also ensure the rationality and safety of patient's medication,promoting the specialization of patient drug use.
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