Chromosome heteromorphisms: do they entail a reproductive risk for male carriers?  

作　　者：Ester Anton Elena Garcia-Guixe Mireia Ramos-Muntada Anna Godo Mireia Sandalinas Joan Blanco 

机构地区：[1]Genetics of Male Fertility Group,Cell Biology Unit,Faculty of Biosciences,Autonomous University of Barcelona,Bellaterra(Cerdanyola del Valles)08193,Spain [2]Reprogenetics Spain,Barcelona 08006,Spain

出　　处：《Asian Journal of Andrology》2020年第5期544-546,共3页亚洲男性学杂志（英文版）

基　　金：(Agency for Management of University and Research Grants,Spain)and UAB C F-180034 grant(Autonomous University of Barcelona).

摘　　要：Dear Editor,Chromosome heteromorphisms are described as variations in size and morphology at specific regions that can be detected through classical banding methods.They are mitotically stable variants usually present in a heterozygous state(only one of the homologous chromosomes is heteromorphic).In humans,the most commonly detected heteromorphisms involve the heterochromatic regions of chromosomes 1,9,16,and Y(designated as lqh,9qh,16qh,and Yqh,respectively),and the short-arms,satellites,or stalks of the acrocentric chromosomes 13,14,15,21,and 22(e.g,for chromosome 13 designated as 13p.13ps,and 13pstk,respectively).Pericentric inversions involving the heterochromatic region of chromosomes l,9,and Y are also frequently observed.

关 键 词：methods. designated chromosomes 

分 类 号：Q343.2[生物学—遗传学] R697[医药卫生—泌尿科学]