Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis  

作　　者：Lu-lu WANG Maria GSHWANDTNER Leopold ECKHART Erwin TSCHACHLER 

机构地区：[1]Department of Dermatology,Research Division of Biology and Pathobiology of the Skin,Medical University of Vienna,Vienna,A-1090,Austria [2]Department of Pediatrics,The University of Hong Kong-Shenzhen Hospital,Shenzhen,518053,China

出　　处：《Current Medical Science》2020年第3期570-573,共4页当代医学科学（英文）

基　　金：This work was supported by the Austrian Science Fund(FWF):V 548-B30 and by a research grant from CE.R.I.E.S,Neuilly,France.

摘　　要：Cerebellar degeneration-related antigen 1(CDR1)was described to be expressed in the nervous system and in different types of cancer tissues.In the present study,we demonstrate that CDR1 is in addition ubiquitously expressed in human epidermis,dermis and isolated skin cells.Both CDR1 mRNA and protein were detected in human skin-derived mast cells,melanocytes,fibroblasts and keratinocytes,suggesting that CDR1 does not have a neuron-specific function.

关 键 词：cerebellar degeneration-related antigen 1 SKIN KERATINOCYTE mast cell 

分 类 号：R37[医药卫生—病原生物学]