基于数据挖掘的治疗新型冠状病毒肺炎中药性味归经规律分析  

Medication Regularities of Traditional Chinese Medicine for treating COVID-19:A datamining-based literatureanalysis

作　　者：赵文翰[1,2] 奚小土[2] 林琳[2] ZHAO Wen-han;XI Xiao-tu;LIN Lin(Guangzhou University of Traditional Chinese Medicine,Guangzhou 510006;the Second Clinical School of Guangzhou University of Traditional Chinese Medicine,Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou 510120)

机构地区：[1]广州中医药大学,广东广州510006 [2]广州中医药大学第二附属医院,广东省中医院,广东广州510120

出　　处：《海南医学院学报》2020年第19期1455-1458,1463,共5页Journal of Hainan Medical University

基　　金：广东省自然科学基金项目(2017A030313724);广东省中医药管理局项目(20181125);广东省中医院周仲瑛学术经验传承工作室。

摘　　要：目的:采用数据挖掘方法研究分析治疗2019年12月发生的新型冠状病毒肺炎(COVID-19)的用药性味和归经分布规律,为临床处方用药提供参考。方法:采集自国家及各省、市、自治区卫生与健康委员会、中医药管理局根据本次疫情的发病情况确立的最新治疗方案中的中药治疗处方,建立数据库,运用SPSS 21.0进行频数统计,分析新冠肺炎用药的药性分布规律。结果:用于治疗新冠肺炎的药物中五味以苦、辛、甘为主;四气以温、寒、平为主;归经以肺经、胃经、脾经和心经为主;辽宁、河北、天津、山东、江苏、上海、浙江、广西等沿海地区及宁夏、山西、湖北、四川、贵州等内陆地区治疗新冠肺炎的中药以温性药物为主;黑龙江、吉林、福建、广东、海南等沿海地区及内蒙古、新疆、北京、陕西、江西、湖南等内陆地区则以寒性药物为主。结论:治疗新冠肺炎的中药归经分布能反映本病“肺-脾-心”的发病转归过程,五味分布反映本病“湿、热、毒、瘀”的病机特点,各地区使用中药的四气分布情况在一定程度上具有地域差异性,体现了中医因地制宜、因时制宜、因人制宜的辩证特点。Objective:To explore distribution regularities of the nature,flavor,and channel entry of traditional Chinese Medicine(TCM)for treating Corona Virus Disease 2019(COVID-19)by data mining in the relevant literature to provide basis for clinical prescriptions.Methods:The database was established by collecting and analyzing the prescriptions to treat the COVID-19 issued by the state and province level administration departments,autonomous regions and municipalities directly under the Central Government were retrieved.The frequencies and the distribution regularities of the nature and flavor of these Chinesemedicines were statistically analyzed by SPSS 21.0.Results:Mostofthemedicationswere bitter,xin,sweet,warm,cold,and plain,entered the lung,stomach,spleen,and heart channel.Warmmedicine were used most frequently in coastal areas such as Liaoning,Hebei,Tianjin,Shandong,Jiangsu,Shanghai,Zhejiang,Guangxi and inland areas such as Ningxia,Shanxi,Hubei,and Sichuan,and Guizhou,while cold medicine were used most incoastal areas such as Heilongjiang,Jilin,Fujian,Guangdong,Hainan and inland areas such as Inner Mongolia,Xinjiang,Beijing,Shanxi,Jiangxi,and Hunan.Conclusions:The medication Regularities of the Nature and Flavor of TCMmight reflect the pathogenesis of COVID-19.TCM use varies by region,reflects the dialectical characteristics of traditional Chinese medicine,treat in accordance with seasonal conditions,local conditions and the patient'sindividuality.

关 键 词：数据挖掘 新型冠状病毒肺炎 中药性味 归经 

分 类 号：R259[医药卫生—中西医结合]