pH响应性聚合物胶束在药物递送系统中的研究进展  

Research Progress of pH Responsive Polymer Micelles in Drug Delivery System

作　　者：李艳艳 毕韵梅[1] LI Yan-yan;BI Yun-mei(Faculty of Chemistry and Chemical Engineering of Yunnan Normal University,Kunming 650500,China)

机构地区：[1]云南师范大学化学化工学院,云南昆明650500

出　　处：《化工管理》2020年第28期109-110,共2页Chemical Engineering Management

基　　金：国家自然科学基金资助项目(No:21564017)。

摘　　要：pH响应性聚合物胶束作为一类重要的智能载体材料,具有粒径小、载药量高、可控释药等优点,在药物特别是抗癌药物递送领域具有广泛的应用前景,文章综述了pH响应性聚合物胶束作为药物载体的优势、两种制备策略和应用研究进展。As an important kind of intelligent carrier materials,pH responsive polymer micelles have the advantages of small particle size,high drug loading and controlled drug release.It has a broad application prospect in the field of drug delivery,especially in the field of anticancer drug delivery.This paper reviews the advantages,two preparation strategies and application research progress of pH responsive polymer micelles as drug carriers.

关 键 词：聚合物胶束 环境刺激响应性 PH响应性 药物载体 

分 类 号：TQ460.4[化学工程—制药化工] TQ317