代谢综合征与血管性认知障碍关系的研究进展  

Advances in the study of metabolic syndrome and vascular cognitive impairment

作　　者：韩芸峰[1] 来璇[2] 杨军 马长城[1] Han Yunfeng;Lai Xuan;Yang Jun;Ma Changcheng(1Department of Neurosurgery,the Third Hospital,Peking University,Beijing 100191,China;Department of Internal Medicine for the Aged,the Third Hospital,Peking University,Beijing 100191,China)

机构地区：[1]北京大学第三医院神经外科,100191 [2]北京大学第三医院老年内科,100191

出　　处：《中华脑血管病杂志（电子版）》2020年第4期234-237,共4页Chinese Journal of Cerebrovascular Diseases(Electronic Edition)

摘　　要：代谢综合征是以中心性肥胖、糖调节受损或糖尿病、脂代谢紊乱及高血压为主要特征,以胰岛素抵抗为共同病理生理基础,合并出现多种代谢性疾病的临床症候群。血管性认知障碍(VCI)是脑血管病变及其危险因素导致的临床卒中或亚临床血管性脑损伤,涉及至少一个认知域受损的临床综合征。本文将综述代谢综合征与VCI之间的关系,并阐述代谢综合征导致VCI的相关机制。Metabolic syndrome is a group of clinical syndromes characterized by central obesity,impaired glucose regulation or diabetes,disorder of lipid metabolism and hypertension.Insulin resistance is the common pathophysiological basis of them.Vascular cognitive impairment(VCI)can be present as a clinical stroke or subclinical vascular brain injury,involving at least one cognitive damaged domain.It is caused by cerebrovascular disease and its risk factors.This article reviewed the relationship between metabolic syndrome and VCI,and the mechanism of metabolic syndrome leading to VCI.

关 键 词：代谢综合征 血管性认知障碍 脑血管病症 

分 类 号：R589[医药卫生—内分泌] R749.13[医药卫生—内科学]