经肠镜下腺瘤切除术联合健脾消积解毒法治疗大肠腺瘤性息肉  

Colonoscopic Adenoma Resection Combined with Jianpi Xiaoji Jiedu Method in Treatment of Colorectal Adenomatous Polyps

作　　者：赵雷[1] 赵玉瑶[1] 赵法新[1] ZHAO Lei;ZHAO Yuyao;ZHAO Faxin(The Affiliated Hospital to Henan Academy of Chinese Medicine,Zhengzhou Henan China 450004)

机构地区：[1]河南省中医药研究院附属医院,河南郑州450004

出　　处：《中医学报》2020年第10期2227-2230,共4页Acta Chinese Medicine

基　　金：国家中医药管理局全国名老中医传承工作室项目{国中医人教发[2014]20号};河南省中医药科学研究专项课题项目(2018ZY2128)。

摘　　要：目的:观察经肠镜下腺瘤切除术联合健脾消积解毒法治疗大肠腺瘤性息肉的临床疗效。方法:106例大肠腺瘤性息肉患者按照随机数字表法分为观察组和对照组各53例。所有患者均行经肠镜下腺瘤切除术,对照组患者给予术后常规治疗,观察组患者在此基础上给予健脾消积解毒法治疗,8周为1个疗程,并随访观察6个月。比较两组患者复发情况,治疗前后中医证候积分、血脂水平及不良反应发生情况。结果:观察组复发率(22.64%)低于对照组(47.17%)(P<0.05)。治疗前,两组患者腹痛、腹胀、便秘、腹泻、口苦、里急后重等中医证候积分比较,差异无统计学意义(P>0.05);治疗后观察组各项积分显著低于对照组,差异有统计学意义(P<0.05)。治疗前,两组患者三酰甘油(triglyceride,TG)、总胆固醇(total cholesterol,TC)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)水平比较,差异无统计学意义(P>0.05);治疗后两组患者TG、TC、LDL-C水平均降低,HDL-C水平均升高,且观察组患者TG、TC、LDL-C水平低于对照组,HDL-C水平高于对照组,差异均有统计学意义(P<0.05)。观察组患者发生腹部疼痛、食少纳呆、体倦乏力、大便溏烂、肛门灼热等不良反应发生率低于对照组,差异均有统计学意义(P<0.05)。结论:经肠镜下腺瘤切除术联合健脾消积解毒法治疗大肠腺瘤性息肉疗效显著,可改善患者血脂水平,减少术后并发症,降低复发率。Objective:To observe the clinical efficacy of colonoscopic adenoma resection combined with Jianpi Xiaoji Jiedu method in treatment of colorectal adenomatous polyps.Methods:106 patients with colorectal adenomatous polyps were divided into observation group and control group with 53 cases in each group according to the random number table method.All patients underwent colonoscopic adenoma resection.Patients in the control group were given conventional postoperative treatment,and patients in the observation group were treated with the method of invigorating the spleen and detoxification on this basis.8 weeks was a course of treatment,and followed up for 6 months.The recurrence of the two groups of patients,the TCM syndrome scores,blood lipid levels and adverse reactions before and after treatment were compared.Results:The recurrence rate of the observation group(22.64%)was lower than that(47.17%)of the control group(P<0.05).Before treatment,there was no significant difference in the scores of TCM syndromes such as abdominal pain,bloating,constipation,diarrhea,bitter mouth,and tenesmus between the two groups of patients(P>0.05);the scores of the observation group were significantly lower than those of the control group after treatment.There is statistical significance(P<0.05).Before treatment,the two groups of patients had triglyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),and low density lipoprotein cholesterol(low density lipoprotein cholesterol).,LDL-C level,the difference was not statistically significant(P>0.05);after treatment,the two groups of patients TG,TC,LDL-C levels decreased,HDL-C levels increased,and the observation group TG,TC The level of LDL-C was lower than that of the control group,and the level of HDL-C was higher than that of the control group.The differences were statistically significant(P<0.05).The incidence of adverse reactions such as abdominal pain,poor appetite and appetite,fatigue,loose stools,and anal burning in the observation group was lower than that in

关 键 词：健脾消积解毒法 经肠镜下腺瘤切除术 大肠腺瘤性息肉 中医证候积分 血脂 中西医结合 

分 类 号：R273.353.4[医药卫生—中西医结合]