莫西沙星与左氧氟沙星治疗老年耐多药肺结核病的效果比较  

Comparison of the effects of moxifloxacin and levofloxacin in the treatment of elderly multi-drug resistant tuberculosis

作　　者：郭庆霞 GUO Qing-xia(Fuxin Infectious Disease Hospital,Fuxin 123000,China)

机构地区：[1]辽宁省阜新市传染病医院,123000

出　　处：《中国现代药物应用》2020年第19期130-131,共2页Chinese Journal of Modern Drug Application

摘　　要：目的比较莫西沙星与左氧氟沙星治疗老年耐多药肺结核病患者的临床效果。方法78例老年耐多药肺结核病患者,随机分为对照组和研究组,各39例。对照组采用左氧氟沙星治疗,研究组采用莫西沙星治疗。比较两组患者的治疗效果及不良反应发生情况。结果研究组治疗总有效率94.87%明显高于对照组的79.49%,差异有统计学意义(P<0.05)。研究组不良反应发生率低于对照组,差异有统计学意义(χ^2=7.222,P<0.05)。结论针对老年耐多药肺结核病患者,莫西沙星治疗效果更优于左氧氟沙星,且安全性较高,值得推广应用。Objective To compare the clinical effect of moxifloxacin and levofloxacin in the treatment of elderly multi-drug resistant tuberculosis.Methods A total of 78 elderly patients with multi-drug resistant tuberculosis were randomly divided into control group and research group,with 39 cases in each group.The control group was treated with levofloxacin,and the research group was treated with moxifloxacin.The therapeutic effect and occurrence of adverse reactions were compared between the two groups.Results The total effective rate of treatment 94.87%of the research group was obviously higher than 79.49%of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse reactions of the research group was lower than that of the control group,and the difference was statistically significant(χ^2=7.222,P<0.05).Conclusion For elderly patients with multi-drug-resistant tuberculosis,moxifloxacin has a better therapeutic effect and higher safety than levofloxacin,which is worthy of promotion and application.

关 键 词：莫西沙星 左氧氟沙星 老年耐多药肺结核病 

分 类 号：R521[医药卫生—内科学]