临床药师干预呼吸内科抗菌药物应用的效果  

Effect of clinical pharmacists intervention on the application of antibiotics in respiratory medicine

作　　者：曹小花[1] 杨海健 卢春霞[1] CAOXiao-hua;YANG Hai-jian;LU Chun-xia(Qidong People’s Hospital,Qidong 226200,China)

机构地区：[1]启东市人民医院,226200

出　　处：《中国现代药物应用》2020年第19期217-219,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探究临床药师干预呼吸内科抗菌药物应用的效果。方法120例呼吸内科住院患者为研究对象,随机分为观察组和对照组,各60例。观察组采用临床药师干预,对照组应用呼吸内科传统用药方式进行治疗,不采用临床药师干预。比较两组患者的抗菌药物应用情况,抗菌药物不合理应用情况、抗感染效果。结果观察组抗菌药物应用率70.0%低于对照组的96.7%,差异具有统计学意义(P<0.05)。观察组应用抗菌药物患者的选药不合理、用药不规范、联合用药不合理、无病源学支持的发生率分别为5.2%、8.6%、10.3%、3.4%,均低于对照组的23.8%、35.7%、28.6%、19.0%,差异均具有统计学意义(P<0.05)。观察组急重症抢救成功率、传染控制率分别为34.5%、48.3%,均高于对照组的16.7%、19.0%,差异均具有统计学意义(P<0.05)。结论对呼吸内科患者采用临床药师干预,可保障抗菌药物用药的合理性以及提高抗菌药物的应用效率,建议临床上推广。Objective To investigate the effect of clinical pharmacists intervention on the application of antibiotics in respiratory medicine. Methods A total of 120 inpatients in respiratory medicine as study subjects were randomly divided into observation group and control group, with 60 cases in each group. The observation group was intervened by clinical pharmacists, while the control group was treated with traditional medicine in respiratory medicine instead of clinical pharmacists intervention. The use of antibiotics, irrational application of antibiotics and anti infection effect were compared between the two groups. Results The application rate of antibiotics 70.0% of the observation group was lower than 96.7% of the control group, and the difference was statistically significant(P<0.05). The incidence of irrational drug selection, nonstandard drug use, irrational combination drug use and no etiological support were found in patients with antimicrobial agents of the observation group were 5.2%, 8.6%, 10.3% and 3.4%, which were lower than 23.8%, 35.7%, 28.6% and 19.0% of the control group, and the difference was statistically significant(P<0.05). The survival rate of critically ill cases and infection control rate of the observation group were 34.5% and 48.3%, which were all higher than 16.7% and 19.0% of the control group, and the difference was statistically significant(P<0.05). Conclusion Clinical pharmacist intervention for patients in respiratory medicine can ensure the rationality of the use of antibacterial drugs and improve the application efficiency of antibacterial drugs. It is recommended to promote clinically.

关 键 词：抗菌药物 临床药师 呼吸内科 应用效果 

分 类 号：R47[医药卫生—护理学]