氨丙啉和托曲珠利抗兔球虫的效果观察  

Observation on the anti-coccidiosis effect of amprolium and to toltrazuril in rabbits

作　　者：刘康雅 王猛 关琛 顾小龙[1] 方素芳[1] 崔平 Liu Kangya;Wang Meng;Guan Chen;Gu Xiaolong;Fang Sufang;Cui Ping(Colloge of Animal Science and Technology,Hebei North University,Hebei Zhangjiakou 075000)

机构地区：[1]河北北方学院动物科技学院,河北张家口075000

出　　处：《现代畜牧兽医》2020年第10期1-3,共3页Modern Journal of Animal Husbandry and Veterinary Medicine

基　　金：河北省教育厅资助重点项目(ZD2018032);河北省自然科学基金和重点基础研究专项(C2019405052)。

摘　　要：试验旨在研究氨丙啉、托曲珠利及其联合用药抗兔艾美耳球虫感染的效果。将30只无球虫兔随机分为5组,Ⅰ组不感染不用药;Ⅱ组感染不用药;Ⅲ组在饮水中连续4 d加入氨丙啉(50 mg/kg体重);Ⅳ组在饮水中连续2 d加入托曲珠利(5 mg/kg体重);Ⅴ组氨丙啉与托曲珠利联合用药,即在饮水中连续4 d加氨丙啉(50 mg/kg体重)、在饮水中连续2 d加托曲珠利(5 mg/kg体重)。结果显示:氨丙啉、托曲珠利及其联合用药均能显著降低每克粪便中的卵囊数(OPG)(P<0.05),有效控制死亡率,基本消除了临床症状,各项指标接近或恢复到正常水平。两种药物及其联合用药均可改善兔球虫病的不良影响,两种药物联合使用的效果更为明显。The experiment was to study the efficacy of amprolium,toltrazuril and their combination in the treatment of rabbit eimeria infection.30 eimeria-free rabbits were randomly divided into five groups:group I was not infected,group II was infected and untreated,group III was given amprolium(50 mg/kg BW)for 4 d,a nd group IV was given toltrazuril(5 mg/kg BW)for 2 d,groupⅤwas the combination of amprolium and toltrazuril which were respectively given in drinking water for 4 consecutive days(50 mg/kg BW)and in drinking water for two consecutive days(5 mg/kg BW).The results indicated that toltrazuril,amprolium and their combined use could significantly reduce OPG(P<0.05),effectively control the mortality of coccidiosis,basically eliminate the clinical symptoms,and the indexes were close to or return to the normal level.Both drugs and their combination improved the adverse effects of rabbit coccidiosis,but the concurrent use of both drugs was more superior.

关 键 词：氨丙啉 托曲珠利 球虫病 兔 

分 类 号：S852.7[农业科学—基础兽医学]