中药中二萜类化学成分分析方法的研究进展  

Research advances on analytical methods for diterpenoids in traditional Chinese medicines

作　　者：徐硕[1] 姜文清[1] 吴学军[1] 徐文峰[1] 金鹏飞[1] XU Shuo;JIANG Wenqing;WU Xuejun;XU Wenfeng;JIN Pengfei(Department of Pharmaceutical Science,Beijing Hospital,National Center of Gerontology,Beijing Key Laboratory of Drug Clinical Risk and Personalized Medication Evaluation,Beijing 100730,China)

机构地区：[1]北京医院药学部,国家老年医学中心,药物临床风险与个体化应用评价北京市重点实验室,北京100730

出　　处：《西北药学杂志》2020年第5期788-790,F0003,共4页Northwest Pharmaceutical Journal

基　　金：国家自然科学基金青年科学基金项目(编号:81303216);北京医院科技新星项目(编号:BJ-2016-039)。

摘　　要：目的了解中药中二萜类化学成分分析方法的研究进展。方法查阅相关文献并归纳总结,综述近年来各种分析技术在中药中二萜类化学成分定性和定量分析中的应用。结果二萜类化合物的定性分析方法包括HPLC法和液相色谱-质谱联用(LC-MS)法;定量分析方法包括紫外-可见分光光度法、HPLC法和LC-MS法,其中紫外-可见分光光度法和HPLC法在定量分析中的应用较多。结论二萜类化学成分的分析方法取得了一定进展,但仍存在一些问题,需要深入探讨。Objective To know about the research progress of analytical methods for diterpenoids in traditional Chinese medicines.Methods The related literatures and the application of various analytical technology in qualitative and quantitative analysis of diterpenoids in traditional Chinese medicines were reviewed and summarized.Results Qualitative analysis methods for diterpenoids include high performance liquid chromatography(HPLC)and liquid chromatography-mass spectrometry(LC-MS);quantitative methods include UV-visible spectrophotometry,HPLC and LC-MS.Among them,UV-visible spectrophotometry and HPLC are widely used in quantitative analysis.Conclusion Although much progress has been made,there are still some problems for further exploration in analytical methods for diterpenoids in traditional Chinese medicines.

关 键 词：二萜类 分析方法 含量测定 中药 

分 类 号：R284[医药卫生—中药学]