戒烟干预联合呼吸锻炼对慢性阻塞性肺疾病稳定期患者肺功能及生活质量的影响  

Influence of smoking cessation combined with breathing exercises on lung function and quality of life of patients with chronic obstructive pulmonary disease during stable disease phase

作　　者：曾军杰[1] 程哲[2] Zeng Junjie;Cheng Zhe(Henan Medical Association,Zhengzhou 450003,China;Department of Respiratory,the First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,China)

机构地区：[1]河南省医学会,郑州450003 [2]郑州大学第一附属医院呼吸科,450052

出　　处：《中国实用医刊》2020年第17期66-69,共4页Chinese Journal of Practical Medicine

摘　　要：目的研究戒烟干预联合呼吸锻炼对慢性阻塞性肺疾病稳定期患者肺功能及生活质量的影响。方法抽取郑州大学第一附属医院2018年3月至2019年3月门诊随访的200例男性慢性阻塞性肺疾病患者为研究对象,按照随机数字表法分为对照组、戒烟组、呼吸锻炼组及戒烟组联合呼吸锻炼组,每组50例。200例患者中失访18例,最终纳入对照组47例,戒烟组45例,呼吸锻炼组43例,戒烟联合呼吸锻炼组47例。对照组给予基础药物治疗,戒烟组和呼吸锻炼组在基础药物治疗基础上分别给予戒烟干预和呼吸锻炼干预,戒烟联合呼吸锻炼组则给予戒烟和呼吸锻炼双重干预。评估患者治疗前和干预3个月后肺功能、改良呼吸困难指数(mMRC)、慢性阻塞性肺疾病评估测试(CAT)评分以及6 min步行距离(6MWD)。结果干预前,四组患者第1秒用力呼气容积(FEV1)占预计值%、FEV1/用力肺活量(FVC)、mMRC、CAT评分及6MWD比较差异未见统计学意义(P>0.05)。干预3个月后,对照组FEV1占预计值%、FEV1/FVC、mMRC、CAT评分及6MWD与干预前比较差异未见统计学意义(P>0.05)。干预3个月后,戒烟组、呼吸锻炼组及戒烟联合呼吸锻炼组患者FEV1占预计值%、FEV1/FVC、mMRC、CAT评分及6MWD均较干预前改善,且戒烟联合呼吸锻炼组上述指标优于戒烟组与呼吸锻炼组(P<0.05)。结论戒烟联合呼吸锻炼可以改善慢性阻塞性肺疾病患者的肺功能和生活质量。Objective To study the effects of smoking cessation combined with breathing exercises on pulmonary function and quality of life in patients with chronic obstructive pulmonary disease(COPD)during stable disease phase.Methods A total of 200 male patients with COPD followed up in outpatient department of the First Affiliated Hospital of Zhengzhou University from March 2018 to March 2019 were selected as research objects.They were divided into control group,smoking cessation group,breathing exercises group and smoking cessation combined breathing exercises group by random number table method,with 50 cases in each group.Ultimately,18 of the 200 patients were lost to follow-up,resulting in 47 cases enrolled in control group,45 cases allocated to smoking cessation,43 cases enrolled in breathing exercises group and 47 cases in smoking cessation combined with breathing exercise group.The control group was given basic drug treatment.The smoking cessation group and the breathing exercise group were given quit smoking and breathing exercise intervention,respectively,based on the basic drug treatment.While the smoking cessation combined with breathing exercises group was given both interventions of quit smoking and breathing exercises,based on the basic drug treatment.Lung function,Modified Medical Research Council(mMRC)scale score,chronic obstructive pulmonary disease assessment test(CAT)score,and 6-minute walking distance(6MWD)of the four groups were evaluated before intervention and 3 months after intervention.Results Before intervention,there was no significant difference in forced expiratory volume in one second(FEV1)as percentage of predicted volume(FEV1pre%),FEV1/forced vital capacity(FVC),mMRC score,CAT score and 6MWD among the four groups(P>0.05).Compared to indexes values before intervention,FEV1pre%,FEV1/FVC,mMRC,CAT score and 6MWD had no significant change in the control group after 3 months of intervention(P>0.05).After 3 months of intervention,FEV1pre%,FEV1/FVC,mMRC,CAT score,and 6MWD in smoking cessation group,

关 键 词：慢性阻塞性肺疾病 稳定期 戒烟 呼吸锻炼 

分 类 号：R563.9[医药卫生—呼吸系统]