抗苗勒管激素在多囊卵巢综合征的应用研究进展  

Research progress on application of anti-mullerian hormone in polycystic ovary syndrome

作　　者：韦霁芸[1] 班婷[1] Wei Jiyun;Ban Ting(Hechi People's Hospital Department of Reproductive Medicin, Hechi, Guangxi 547000)

机构地区：[1]广西河池市人民医院生殖医学科,广西河池547000

出　　处：《中外女性健康研究》2020年第19期14-15,24,共3页Women＇s Health Research

基　　金：河池市科学研究与技术开发计划项目,项目编号:河科转1623-25;项目名称:抗苗勒管激素在预测PCOS患者使用克罗米芬促排卵反应性的相关研究。

摘　　要：抗苗勒管激素(AMH)是由卵巢上发现的早期窦状卵泡的颗粒细胞产生的一种糖蛋白二聚体。AMH的水平与窦卵泡数量相关,是评价卵巢储备的良好指标,是预测卵巢储备功能和促排卵治疗卵巢反应性的有效指标。多囊卵巢综合征(PCOS)是最常见的女性生殖内分泌疾病,常合并肥胖、代谢综合征、胰岛素抵抗等,严重威胁女性健康。PCOS分泌过量的AMH,直接影响患者激素水平,诱导PCOS的发生。现在对AMH与PCOS相关内分泌指标、临床特征和鉴别诊断等方面做如下综述。Anti-mullerian hormone(AMH)is a glycoprotein dimer produced by granulosa cells of early sinusoidal follicles found in the ovary.AMH level is related to the number of sinus follicles,which is a good indicator to evaluate ovarian reserve,to predict ovarian reserve function and to promote ovulation in the treatment of ovarian reactivity.Cystic ovary syndrome(PCOS)is the most common female reproductive endocrine diseases,often associated with obesity,metabolic syndrome,insulin resistance and other serious threats to women's health.Excessive AMH secretion of PCOS directly affects the hormone level of patients and induces the occurrence of PCOS.The endocrine index,clinical features and differential diagnosis of AMH and PCOS are summarized as follows.

关 键 词：抗苗勒管激素 多囊卵巢综合征 内分泌指标 临床特征 鉴别诊断 

分 类 号：R71[医药卫生—妇产科学]