化疗患者味觉改变的个体化干预及效果评价  

Individualized Taste Intervention on Taste Changes and Quality of Life in Patients Undergoing Chemotherapy

作　　者：张丽燕[1] 国仁秀 张婷婷 梁亚茹 许晨辉[1] ZHANG Liyan;GUO Renxiu;ZHANG Tingting;LIANG Yaru;XU Chenhti(Department of Gastroenterol-ogy and Oncology,Beijing Cancer Hospital,Beijing Institute for Cancer Research,Beijing 100142,China)

机构地区：[1]北京大学肿瘤医院暨北京市肿瘤防治研究所消化肿瘤内科,北京100142

出　　处：《解放军护理杂志》2020年第9期26-29,共4页Nursing Journal of Chinese People's Liberation Army

摘　　要：目的探讨个体化干预对化疗患者味觉改变(chemotherapy-induced taste alteration,CKTA)及生活质量的影响。方法便利抽样选取2018年9月至2019年7某医院消化肿瘤内科出现味觉改变的患者,按入院时间先后分为对照组和干预组,对照组行常规护理,干预组在充分评估的基础上进行为期3个月的个体化干预。干预前后采用中文版化疗相关味觉改变量表(the chemotherapy-induced taste alternation scale,CITAS)和生活质量核心问卷(the quality of life questionaire-core 30,QLQ-C30)对两组患者进行问卷调查。结果干预后,干预组患者CiTAS总分明显降低,尤其是味觉异常及进食困扰等维度问题改善明显,且总体生活质量,躯体功能,社会功能、情绪功能有所提升,疲乏、恶心呕吐、食欲丧失和便秘等症状明显改善(P<0.01),与对照组比较差异均有统计学意义(均P<0.05)。结论应用个体化味觉干预,可有效改善化疗患者味觉改变的程度,提升患者生活质量。Objective To investigate the effect of individual management on chemotherapy-induced tastealteration(CiTA)and the quality of life in patients with chemotherapy.Methods By the convenience sam-pling method,patients with CiTA from September 2018 to July 2019 were selected and divided into controlgroup and observation group.The control group received routine care,and the intervention group conductedtargeted individualized management for 3 months based on full assessment.Before and after the interven-tion,the chemotherapy-induced taste alternation scale(CTAS)and the quality of life questionnaire-core 30(QLQ-C30)were used to investigate the two groups of patients,Results After the intervention,the totalscore of CiTA in the intervention group was significantly reduced,especially the dimension problems of ab-normal taste and eating disturbance were significantly improved;the overall quality of life,physical func-tion,social function and emotional function were improved;the symptoms of fatigue,nausea and vomiting,loss of appetite and constipation were significantly improved(P<0.01),wiich were significantly betterthan those of the control group(all P<0.05).Conclusions The application of individualized taste inter-vention can effectively improve the degree of taste change of chemotherapy patients and improve their qual-ity of life.

关 键 词：个体化干预 化疗相关味觉改变 生活质量 

分 类 号：R473.73[医药卫生—护理学]