中药内服联合激素吸入治疗支气管哮喘缓解期肺脾气虚证患儿Meta分析  

Meta-Analysis on Oral Administration of Chinese Herbal Medicine Combined with Hormone Inhalation for Children with Bronchial Asthma in Remission Stage with Lung-Spleen Qi Deficiency Syndrome

作　　者：寇晓华 陈慧[2] 李雯雯 KOU Xiaohua;CHEN Hui;LI Wenwen

机构地区：[1]天津中医药大学,天津300073 [2]天津中医药大学第二附属医院,天津300150

出　　处：《新中医》2020年第17期13-16,共4页New Chinese Medicine

基　　金：天津市卫生计生行业高层次人才选拔培养工程建设项目(津人才[2017]18号)。

摘　　要：目的:利用数据挖掘的方法验证中药内服联合激素吸入治疗支气管哮喘缓解期肺脾气虚证患儿的疗效。方法:收集已发表的关于中药联合激素(试验组)对比激素(对照组)治疗支气管哮喘缓解期肺脾气虚证患儿的临床文献,筛选后运用RevMan 5.3软件对2组有效率、总症状积分、第1秒用力呼气容积(FEV1)、哮喘发作次数进行Meta分析。结果:共纳入17个临床随机对照试验,1 569例患者。Meta分析结果显示,与对照组比较,试验组患者临床总有效率较高,哮喘发作次数及总症状积分较低,差异均有统计学意义(P<0.05);FEV1较高,但差异无统计学意义。结论:对于支气管哮喘缓解期肺脾气虚证的患儿,中药内服联合激素吸入较单纯吸入激素效果更佳。Objective: To verify the curative effect of oral administration of Chinese herbal medicine combined with hormone inhalation for children with bronchial asthma in remission stage with lung-spleen qi deficiency syndrome by the method of data mining. Methods:Published clinical literature on treating children with bronchial asthma in remission stage with lung-spleen qi deficiency syndrome were selected, in which the experiment group treated with Chinese herbal medicine combined with hormone and the control group treated with hormone were compared. After screening, Metaanalysis on the effective rates,total symptom scores,the forced expiratory volume in one second(FEV1) and the numbers of asthma attacks in the two groups was conducted by RevMan 5.3 software. Results: A total of 17 clinical randomized controlled trials were included,with 1 569 cases of patients. Meta-analysis results showed that when compared with those in the control group,the total clinical effective rate in the experiment group was higher and the number of asthma attacks as well as the total symptom scores were lower,differences being significant(P<0.05);FEV1 was higher,but there was no significance in the difference. Conclusion: For the children with bronchial asthma in remission stage with lung-spleen qi deficiency syndrome,the therapy of oral administration of Chinese herbal medicine combined with hormone inhalation has better effect than that of inhaling hormone alone.

关 键 词：支气管哮喘缓解期 肺脾气虚证 激素吸入 中药内服 META分析 

分 类 号：R562.25[医药卫生—呼吸系统]