舒芬太尼麻醉在老年患者全麻诱导期对血流动力学的影响  

Effects of Sufentanil anesthesia on hemodynamics in elderly patients during induction of general anesthesia

作　　者：周伟[1] ZHOU Wei(Department of Surgical Anesthesiology,General Hospital of Puyang Oilfield,Puyang,Henan 457001,China)

机构地区：[1]濮阳市油田总医院手术麻醉科,河南濮阳457001

出　　处：《医药论坛杂志》2020年第9期81-84,共4页Journal of Medical Forum

摘　　要：目的探讨舒芬太尼麻醉在老年患者全麻诱导期对血流动力学的影响。方法选取2017年6月—2019年6月于濮阳市油田总医院就诊治疗的老年全麻手术患者112例,根据麻醉用药方案分为对照组(56例)和研究组(56例),给予对照组芬太尼麻醉诱导,给予研究组舒芬太尼麻醉诱导,比较两组于麻醉诱导前(T0)、气管插管时(T1)、气管插管1 min后(T2)、气管插管5 min后(T3)、气管插管10 min后(T4)的血流动力学指标水平变化。结果两组从T0至T1血流动力学指标变化趋势均表现为显著下降,研究组从T1至T2的变化趋势表现为显著上升,从T2至T4的变化趋势则表现为缓慢下降;对照组从T1至T2 HR、MAP、SBP的变化趋势表现为略有上升而DBP则呈显著上升,从T2至T3的变化趋势则表现为显著上升,从T3至T4 HR、MAP、DBP的变化趋势表现为略有上升而SBP则呈显著上升。于T0时,两组患者血流动力学指标比较,均无显著差异(P>0.05);T1时,两组患者血流动力学指标均明显低于T0,且研究组MAP与DBP为(79.01±6.98)和(73.68±6.53),均明显高于对照组的(71.53±6.47)和(70.19±6.32),差异有统计学意义(P<0.05);T2时,研究组患者血流动力学指标均明显高于T0、T1,对照组血流动力学指标均明显低于T0,且研究组血流动力学指标均明显低于对照组,差异有统计学意义(P<0.05);T3时,研究组血流动力学指标均明显高于T1,对照组血流动力学指标均明显高于T1、T2,且研究组血流动力学指标均明显高于对照组,差异有统计学意义(P<0.05);T4时,研究组血流动力学指标均明显高于T1且DBP(81.84±6.13)明显低于T2,对照组血流动力学指标均明显高于T1、T2且MAP(77.15±6.59)明显低于T0,而SBP(119.62±9.85)明显高于T3,且研究组MAP、SBP、DBP均明显高于对照组,差异有统计学意义(P<0.05)。结论于老年患者全麻诱导期应用舒芬太尼麻醉对患者心率、血压的影响较小,更有利于保持血流动力学�Objective To investigate the effect of sufentanil anesthesia on hemodynamics in elderly patients during the induction period of general anesthesia.Methods From June 2017 to June 2019 in our hospital treatment in elderly patients with general anesthesia surgery of 112 cases,according to the scheme of anesthetic drugs were divided into control group(56 cases)and group(56 cases),giving the control group of fentanyl anesthesia induction,gives the team sufentanil anesthesia induction,compare two groups(T0)before anesthesia induction,endotracheal intubation(T1),1 min after endotracheal intubation(T2),endotracheal intubation(T3)after 5 min,10 min after endotracheal intubation hemodynamic parameters(T4)level changes.Results compared with T1,the hemodynamic indexes of the two groups were significantly higher at T0(P<0.05).Compared with T2,the hemodynamic indexes of the experimental group were significantly lower at T0 and T1,while those of the control group were significantly higher at T0,with significant differences(P<0.05).Compared with T3,both groups had significantly lower hemodynamic indexes at T1,and the control group had significantly lower hemodynamic indexes at T2,with significant differences(P<0.05).Compared with T4,the MAP in the control group was significantly higher at T0,the hemodynamic indexes in both groups were significantly lower at T1,the DBP in the study group was significantly lower at T2,the hemodynamic indexes in the control group were significantly lower at T2,the SBP in the control group was significantly lower at T3,and the SBP in the study group was significantly higher than that in the control group,with significant differences(P<0.05).Compared with the control group,MAP and DBP were significantly higher in the study group at T1,T3 and T4,HR and SBP were significantly higher at T3,SBP was significantly higher at T4,and the hemodynamic indexes were significantly lower at T2,with significant differences(P<0.05).Conclusion the effect of sufentanil anesthesia on the heart rate and blood pressure of

关 键 词：舒芬太尼 麻醉 老年人 全麻诱导期 血流动力学 

分 类 号：R614[医药卫生—麻醉学]