多囊卵巢综合征患者脾虚证对内分泌代谢异常的影响  

Effect of Spleen Deficiency Syndrome on Endocrine and Metabolic Abnormalities in Patients with Polycystic Ovary Syndrome

作　　者：刘美枝 LIU Meizhi(The Third People’s Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fuzhou 350108,China)

机构地区：[1]福建中医药大学附属第三人民医院,福建福州350108

出　　处：《中外医学研究》2020年第26期181-183,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析多囊卵巢综合征患者脾虚证对内分泌代谢异常的影响。方法:选取2017年11月-2018年11月笔者所在医院收治的82例多囊卵巢综合征患者,以患者病情不同分为观察组A(脾虚证)、观察组B(非脾虚证),各41例,同时选取健康体检人群41例作为对照组,对各组内分泌代谢指标进行检验。结果:观察组A的LH、FSH、PRL、E2均低于观察组B及对照组,差异均有统计学意义(P<0.05),观察组B及对照组各指标比较差异无统计学意义(P>0.05);观察组A的FPG、2 h PG、HOMA-IR均高于观察组B及对照组,差异均有统计学意义(P<0.05),观察组B及对照组各指标比较差异无统计学意义(P>0.05);观察组A的TC、TG、LDL-C均高于观察组B及对照组,HDL-C均低于观察组B及对照组,差异均有统计学意义(P<0.05),观察组B及对照组各指标比较差异均无统计学意义(P>0.05)。结论:多囊卵巢综合征脾虚证患者,均伴有性激素、血糖及血脂指标等内分泌代谢异常,非脾虚证患者,无上述异常。临床可通过检测内分泌代谢指标的方式,鉴别脾虚证,指导临床制定治疗方案。Objective:To analyze the effect of spleen deficiency syndrome on endocrine and metabolic abnormalities in patients with polycystic ovary syndrome(PCOS).Method:A total of 82 patients with polycystic ovary syndrome admitted to the author’s hospital from November 2017 to November 2018 were selected and divided into the observation group A(syndrome of spleen deficiency)and the observation group B(non-syndrome of spleen deficiency)according to their different conditions,with 41 patients in each group.At the same time,41 healthy people were selected as the control group,the endocrine and metabolic indexes of each group were tested.Result:The LH,FSH,PRL and E2 in the observation group A were all lower than those in the observation group B and the control group,the differences were statistically significant(P<0.05),while there was no statistically significant difference between the indicators in the observation group B and the control group(P>0.05).The FPG,2 h PG and HOMA-IR in the observation group A were all higher than those in the observation group B and the control group,the differences were statistically significant(P<0.05),while there were no statistically significant differences between the indicators in the observation group B and the control group(P>0.05).The TC,TG and LDL-C in the observation group A were all higher than those in the observation group B and the control group,while HDL-C was lower than that in the observation group B and the control group,the differences were statistically significant(P<0.05),there were no statistically significant differences between the indicators in the observation group B and the control group(P>0.05).Conclusion:Polycystic ovary syndrome patients with spleen deficiency syndrome are associated with abnormal endocrine metabolism such as sex hormone,blood glucose and blood lipid,but not in patients without spleen deficiency syndrome.Clinical diagnosis of spleen deficiency syndrome can be made by detecting endocrine and metabolic indexes,which can guide clinical treatment.

关 键 词：多囊卵巢综合征 脾虚证 内分泌代谢异常 

分 类 号：R711.75[医药卫生—妇产科学]