颈椎病并发脊髓空洞的系统性文献分析  

Systematic literature analysis of cervical spondylosis complicated with syringomyelia

作　　者：郜顺兴[1] 石家晓 王军[1] 陶晓冰[1] GAO Shun-xing;SHI Jia-xiao;WANG Jun;Tao Xiao-bing(Cangzhou Hospital of Traditional Chinese and Western Medicine,Cangzhou,Hebei 061001,China)

机构地区：[1]河北省沧州中西医结合医院,河北沧州061001

出　　处：《颈腰痛杂志》2020年第5期523-526,530,共5页The Journal of Cervicodynia and Lumbodynia

基　　金：宁夏回族自治区自然科学基金(编号:NZ16212)。

摘　　要：目的分析颈椎病并发脊髓空洞的发病机制、临床症状、诊断及治疗方式、预后转归情况。方法在PubMed及EBSCO Medline Complete全文数据库中检索“cervical spondylosis;Syringomyelia”,在中国知网、万方、维普数据等中文数据库检索“颈椎病;脊髓空洞”,时间节点选取1980~2019年,所有被检索的文献及参考文献均用于分析,经文题、摘要、全文内容二次筛选,将所涉及的颈椎病并发脊髓空洞患者作为研究对象,收集每例患者的发病年龄、性别、症状、手术方式、随访时间、影像学等资料,采用系统分析的方法对数据进行分项研究。结果共筛选出9篇文献11例患者纳入研究,其中女性4例,男性7例,年龄28-81岁,中位年龄62岁。11例患者中,1例未行手术治疗、未提供随访情况;另10例均行颈椎手术治疗,术后神经功能均有不同程度改善(100%),其中7例术后脊髓空洞消退或消失(70%),2例术后脊髓空洞未见明显改变(20%),1例术后脊髓空洞程度增加(10%)。结论对于颈椎病并发脊髓空洞的患者,如排除Chiari畸形等疾病,影像学存在脊髓受压征,行颈椎减压稳定手术可以有效控制并逆转脊髓空洞发展。Objective To analyze the pathogenesis,clinical symptoms,diagnosis,treatment and prognosis of cervical spondylosis complicated with syringomyelia. Methods To search for " cervical spondylosis;syringomyelia" in PubMed and EBSCO MEDLINE complete full-text databases,and " cervical spondylosis;syringomyelia" in Chinese databases of CNKI,Wanfang and VIP,and select the time node From 1980 to 2019,all the retrieved literatures and references were used for analysis. After the second screening of text,abstract and full text,the patients with cervical spondylosis complicated with syringomyelia were taken as the research subjects. The age,gender,symptoms,operation methods,follow-up time,imaging and other data of each patient were collected,and the data were divided into sub items by systematic analysis Results A total of 9 articles were selected and 11 patients were included in the study,including 4 women,7 men,aged 28-81 years old,median age 62 years old. Among the 11 patients,1 patient did not receive surgical treatment and did not provide follow-up information. The other 10 patients received cervical surgery,and the neurological function improved in varying degrees( 100%),including 7 cases of disappearance of syringomyelia( 70%),2 cases of syringomyelia did not change significantly( 20%),and 1 case of increase in syringomyelia( 10%). Conclusion For the patients with cervical spondylosis complicated with syringomyelia,such as excluding Chiari malformation and other diseases,there is a sign of spinal cord compression in the neck. The operation of cervical decompression and stabilization can effectively control and reverse the development of syringomyelia.

关 键 词：颈椎病 脊髓空洞 文献分析 

分 类 号：R681.5[医药卫生—骨科学]