聚合酶链反应对女性生殖道感染解脲支原体及沙眼衣原体检测价值分析  

Value of Polymerase Chain Reaction(PCR) in Detecting Ureaplasma Urealyticum and Chlamydia Trachomatis in Female Genital Tract Infection

作　　者：丘玉辉 QIU Yu-hui(Department of Clinical Laboratory,Jiexi People’s Hospital,Jiexi,Guangdong,515400,China)

机构地区：[1]揭西县人民医院,广东揭西515400

出　　处：《中国初级卫生保健》2020年第9期57-59,共3页Chinese Primary Health Care

摘　　要：目的分析聚合酶链反应(PCR)在女性生殖道解脲支原体(Uu)、沙眼衣原体(Ct)感染检测中应用的价值。方法选取2019年1-6月在揭西县人民医院就诊并接受治疗的205例女性生殖道感染患者,以PCR检测Uu、Ct,分析Uu、Ct感染情况、不同年龄段感染率及治疗后Uu、Ct和Uu+Ct阳性率情况。结果女性生殖道感染患者中,Uu、Ct感染率为68.78%,其中单独Uu感染率高达52.20%,高于单独Ct感染率(3.90%)、Uu+Ct感染率(12.68%),差异有统计学意义(P<0.05);年龄≤30岁女性生殖道Uu、Ct和Uu+Ct感染率最高,分别为58.54%、6.10%和18.29%,年龄>50岁女性生殖道Uu、Ct和Uu+Ct感染率最低,分别为23.08%、0.00%和0.00%,女性生殖道Uu、Ct和Uu+Ct感染率各年龄段比较无统计学意义(P>0.05);治疗后3个月205例患者Uu、Ct和Uu+Ct阳性率与入院时比较均明显降低,差异有统计学意义(P<0.05)。结论女性生殖道Uu感染率高于Ct感染率,≤30岁女性是Uu、Ct感染的高发人群,Uu、Ct感染有随女性年龄增长而递减的趋势,PCR能够对Uu、Ct感染进行动态监测,指导临床治疗,值得推广。OBJECTIVE To analyze the value of PCR in the detection of Ureaplasma urealyticum(Uu) and Chlamydia trachomatis(Ct)infection in female genital tract. METHODS 205 female patients with genital tract infection treated in target hospital from January to June 2019 were selected to detect Uu and Ct by PCR. The infection of Uu and Ct, the infection rate of different ages and the positive rates of Uu, Ct, Uu + Ct after treatment were analyzed. RESULTS The infection rate of Uu and Ct was 68.78% in female patients with genital tract infection, and the infection rate of Uu alone was 52.20%, higher than that of Ct alone(3.90%), Uu + Ct alone(12.68%),the difference was statistically significant(P<0.05);Uu, Ct, Uu + Ct infection rates of female genital tracts aged 30 years or younger were 58.54%, 6.10%, 18.29%. The lowest Uu, Ct, Uu + Ct infection rates of female genital tract above 50 years old were 23.08%,0.00%, and 0.00%, respectively. The female reproductive tract Uu, Ct, Uu + Ct infection rates were not statistically significant in all age groups(P>0.05). The positive rates of Uu, Ct, Uu + Ct in 205 patients 3 months after treatment were significantly lower than those at admission, and the difference was statistically significant(P<0.05). CONCLUSION The infection rate of Uu in female reproductive tract was higher than that of Ct. Female under 30 years old were the high incidence population of Uu and Ct infection. Uu and Ct infection tended to decrease with the increase of women’s age, PCR could monitor the infection of Uu and Ct dynamically and guide the clinical treatment, which was worth popularizing.

关 键 词：聚合酶链反应 生殖道感染 解脲支原体 沙眼衣原体 

分 类 号：R711[医药卫生—妇产科学]