平衡针灸联合左旋氨氯地平降压及纠正非杓型高血压的临床研究  

Clinical study of balanced acupuncture combined with levamlodipine for lowering high blood pressure and correcting non-dipper hypertension

作　　者：杨亚梅[1] 赵卫国[1] 王宏业 张海燕[1] 娄满[1] Yang Yamei;Zhao Weiguo;Wang Hongye;Zhang Haiyan;Lou Man(Department of Traditional Chinese Medicine,Hengshui People's Hospital(Hebei Harrison International Peace Hospital),Hengshui 053000,Hebei,China)

机构地区：[1]衡水市人民医院(河北省哈励逊国际和平医院)中医科,河北衡水053000

出　　处：《中国中西医结合急救杂志》2020年第5期582-585,共4页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：河北省中医药管理局中医药类科研计划课题(2019356)。

摘　　要：目的 探讨平衡针灸联合左旋氨氯地平治疗非杓型高血压的临床疗效及对血压节律的影响.方法 采用前瞻性研究方法,选择2018年8月至2019年12月河北省哈励逊国际和平医院收治的200例非杓型高血压患者作为研究对象,将患者分为对照组和平衡针灸组,每组100例.对照组晨服(07:00)左旋氨氯地平2.5mg治疗;平衡针灸组在对照组基础上晚间加用平衡针灸针刺降压穴治疗1次;两组均治疗3周.比较两组治疗后24h血压水平,并记录不良反应发生情况.结果 治疗后两组血压及24h动态血压水平均明显低于治疗前,平衡针灸组动态血压达标率明显高于对照组〔89%(89/100)比61%(61/100),P<0.05〕;两组治疗后诊室收缩压(SBP)、诊室舒张压(DBP)、24h平均SBP(24hSBP)、24h平均DBP(24hDBP)、白昼平均SBP(dSBP)、白昼平均DBP(dDBP)、夜间平均SBP(nSBP)、夜间平均DBP(nDBP)均较治疗前明显降低〔对照组:诊室SBP(mmHg,1mmHg≈0.133kPa)为138.6±7.4比149.2±8.2,诊室DBP(mmHg)为87.3±6.7比96.6±7.4,24hSBP(mmHg)为134.7±7.3比143.1±6.6,24hDBP(mmHg)为84.2±4.5比92.3±5.9,dSBP(mmHg)为137.3±6.3比146.4±7.3,dDBP(mmHg)为87.4±5.2比94.7±5.8,nSBP(mmHg)为132.7±4.7比139.5±6.2,nDBP(mmHg)为80.3±3.7比91.5±4.3;平衡针灸组:诊室SBP(mmHg)为136.3±8.3比150.1±9.1,诊室DBP(mmHg)为86.4±5.8比97.3±6.3,24hSBP(mmHg)为128.3±6.3比142.8±7.5,24hDBP(mmHg)为78.9±5.7比93.5±6.5,dSBP(mmHg)为135.2±4.5比147.9±8.4,dDBP(mmHg)为83.6±4.2比93.2±6.7,nSBP(mmHg)为124.3±3.6比138.4±5.1,nDBP(mmHg)为74.0±3.3比90.5±4.6,均P<0.05〕,且平衡针灸组24hSBP(mmHg:128.3±6.3比134.7±7.3)和nSBP(mmHg:124.3±3.6比132.7±4.7)均明显低于对照组(均P<0.05);两组治疗后其余指标比较差异均无统计学意义(均P>0.05).两组治疗后夜间SBP下降率(SBPF)均较治疗前升高,且平衡针灸组治疗后SBPF明显高于对照组〔(10.6±2.7)%比(8.8±3.1)%,P<0.05〕.平衡针灸组治疗后非杓型高血压转变为杓型的比例明�Objective To investigale the elinical fficacy of balanced acupuncture combined with levamlodipine in the treatment of non-dipper hypertension and its effect on blood pressure cireadian rhythm.Methods Using prospective study method,the 200 patients with non-dipper hypertension in Hebei Harrison Interational Peace Hospital during August 2018 to December 2019 were selected as research objects,and they were divided into a control group and a balance acupuneture group,each group 100 cases.The patients in control group were given levamlodipine 2.5 mg in the moring(07:00),and patients in balanced acupuncture group were treated with balanced acupuneture once at night on the basis of measure in control group.Both groups were treated for 3 weeks.In the two groups,the blood pressure levels after 24 h of treatment were compared,and the ineidences of adverse reactions were recorded.Results Afer treatmenl,the blood pressure and 24-hour ambulatory blood pressure levels in Iwo groups were significantly lower than those before treatment,and the tolal eleetive rale of 24h ambulatory blood pressure reaching sltandlard level in balance acupuncture group was significanly higher than that in control group[89%(89/100)vs.61%(61/100),P<0.05].The systolie blood pressure in elinical room(SBP),diastolie blood pressure in elinical room(DBP),24-hour mean SBP(24-hour SBP).24-hour mean DBP(24-hour DBP),dayime average SBP(dSBP),dayime average DBP(dDBP).night average SBP(nSBP),and night mean DBP(mDBP)afer trealment were significantly lower than those before treatment in the two groups[control group:clinical room SBP(mmHg.1 mmHg≈0.133 kPa):138.6±7.4 vs.149.2±8.2.elinical room DBP(mmHg):87.3±6.7 vs.96.6±7.4,24 h SBP(mmHg):134.7±7.3 vs.143.1±6.6,24 h DBP(mmHg):84.2±4.5 vs.92.3±5.9,dSBP(mmHg):137.3±6.3 vs.146.4±7.3.dDBP(mmHg):87.4±5.2 vs.94.7±5.8,nSBP(mmHg):132.7±4.7 vs.139.5±6.2.nDBP(mmHg):80.3±3.7 vs.91.5±4.3;balance acupuncture group:clinieal room SBP(mmHg):136.3±8.3 vs.150.1±9.1,clinical room DBP(mmHg):86.4±5.8 ve.97.3±6.3,2

关 键 词：平衡针灸 左旋氨氯地平 非杓型高血压 血压节律 

分 类 号：R54[医药卫生—心血管疾病]