针刺与艾灸治疗慢性萎缩性胃炎的多中心前瞻性临床研究  

Acupuncture and Moxibustion in the Treatment of Chronic Atrophic Gastritis:A Multicenter Prospective Cohort Study

作　　者：范丽红 方园[1] 黄河 曹佳男[1] 欧阳里知[1] 刘密 常小荣[1] FAN Lihong;FANG Yuan;HUANG He;CAO Jianan;OUYANG Lizhi;LIU Mi;CHANG Xiaorong(College of Acupuncture-Moxibustion and Tuina,Hunan University of Chinese Medicine,Changsha,Hunan 410208,China;Changsha Social Work College,Changsha,Hunan 410000,China;Liuyang City Traditional Chinese Medicine Hospital,Liuyang,Hunan 410300,China)

机构地区：[1]湖南中医药大学针灸推拿学院,湖南长沙410208 [2]长沙民政职业技术学院,湖南长沙410208 [3]浏阳市中医医院,湖南浏阳410300

出　　处：《湖南中医药大学学报》2020年第9期1060-1064,共5页Journal of Hunan University of Chinese Medicine

基　　金：国家重点基础研究发展计划(973计划)项目(2015CB554502);国家自然科学基金项目(81574082)。

摘　　要：目的观察针刺与艾灸治疗慢性萎缩性胃炎(chronic atrophic gastritis,CAG)的临床疗效。方法将150例CAG患者随机分为针刺组、艾灸组及药物组,每组50例。针刺组与艾灸组均取主穴足三里、中脘、内关,肝胃不和型配太冲、阳陵泉,脾胃虚寒型配关元、气海;药物组口服维酶素片,一次4~6片,每日3次。3组均连续治疗8周,分别于治疗前、治疗后、治疗后第16周随访观察临床症状积分、中医证候积分。结果各组患者在治疗后、治疗后第16周随访,临床症状积分均较治疗前下降(P<0.05);治疗8周,各组患者间评分两两比较,差异均无统计学意义(P>0.05);治疗后第16周随访,与药物组相比,针刺组与艾灸组的临床症状积分均降低,差异有统计学意义(P<0.05),针刺组与艾灸组相比临床症状积分差异无统计学意义(P>0.05)。同一证型中医证候积分治疗前后比较,脾胃虚寒型的艾灸组治疗后中医证候积分低于针刺组与药物组(P<0.05),肝胃不和型的针刺组中医证候积分低于艾灸组与药物组(P<0.05)。结论针刺、艾灸及药物治疗均能改善CAG患者的症状,针刺与艾灸治疗的远期效果更佳,且艾灸对脾胃虚寒型CAG效果更好,针刺对肝胃不和型CAG更具优势。Objective To observe the clinical effect of acupuncture and moxibustion on chronic atrophic gastritis(CAG).Methods A total of 150 patients with CAG were randomized into a acupuncture group,a moxibustion group and a drug group,with 50 cases in each group.The acupuncture group and the moxibustion group took the main points of Zusanli(ST36),Zhongwan(RN12),Neiguan(PC6).Patients with liver-stomach disharmony were treated plus Taichong(LR3)and Yanglingquan(GB34).Those with deficient cold of spleen-stomach were added Guanyuan(RN4)and Qihai(RN6).In the drug group,oral vitasin tablets were taken 4-6 tablets per time,3 times a day.Each group was treated continuously for 8 weeks.The scores of clinical symptom and TCM syndrome score were observed in the 3 groups before treatment,after 8 weeks of treatment and 24 weeks of inclusion follow-up.Results After 8 weeks of treatment and 24 weeks of inclusion follow-up,the scores of clinical symptom in each were decreased compared with before treatment(P<0.05).After 8 weeks of treatment,pairwise comparisons of scores between each group showed no statistical significance(P>0.05).In 24 weeks of inclusion follow-up,the scores of clinical symptom in the acupuncture group and the moxibustion group were decreased than the drug group,and the difference was statistically significant(P<0.05).There was no statistical significance in comparing the scores of the acupuncture group and the moxibustion group(P>0.05).Compared with the groups of the scores of same TCM syndrome of patients,those with deficiency cold of spleen-stomach syndrome in the moxibustion group was lower than that in the acupuncture group and the durg group(P<0.05).The TCM syndrome scores of patients with liver-stomach disharmony in the acupuncture group was lower than that in the moxibustion group and the drug gourp(P<0.05).Conclusion Acupuncture,moxibustion and drug treatment can effectively improve the symptoms of CAG patients,and the long-term efficacy is much better for acupuncture and moxibustion.Moreover,moxibustion has b

关 键 词：慢性萎缩性胃炎 针刺 艾灸 脾胃虚寒型 肝胃不和型 足三里 中脘 内关 

分 类 号：R245[医药卫生—针灸推拿学]