发热伴咳嗽咳痰患儿应用痰热清注射液临床观察及效果分析  

Clinical observation and effect analysis of Tanreqing Injection in fever children with cough and expectoration

作　　者：沈艳红[1] 张丽娜[1] 黄璐 陈晓[1] 赵线 万红[1] SHEN Yan-hong;ZHANG Li-na;HUANG Lu;CHEN Xiao;ZHAO Xian;WAN Hong(Department of Pediatrics,the First Affiliated Hospital of Nanchang University,Jiangxi Province,Nanchang330006,China)

机构地区：[1]南昌大学第一附属医院儿科,江西南昌330006

出　　处：《中国当代医药》2020年第27期86-88,92,共4页China Modern Medicine

基　　金：江西省中医药科研课题(2019B006)。

摘　　要：目的探讨发热伴咳嗽咳痰患儿应用痰热清注射液治疗的临床效果。方法选取2018年6月~2019年12月在我院就诊的120例发热伴咳嗽咳痰患儿作为研究对象,采用随机数字表法将其分为对照组和实验组,每组各60例。对照组患儿采用常规抗病毒药物治疗,实验组患儿采用常规抗病毒药物+痰热清注射液治疗。比较两组患儿的临床疗效、咳痰缓解时间、咳嗽缓解时间、体温恢复时间,C反应蛋白(CRP)、白细胞计数(WBC)、中性粒细胞比率。结果实验组患儿的治疗总有效率高于对照组,差异有统计学意义(P<0.05);实验组患儿的咳痰缓解时间、咳嗽缓解时间、体温恢复时间均短于对照组,差异有统计学意义(P<0.05);两组患儿治疗后的CRP、WBC、中性粒细胞比率水平均低于治疗前,差异有统计学意义(P<0.05);治疗后,实验组患儿的CRP、WBC、中性粒细胞比率水平均低于对照组,差异有统计学意义(P<0.05)。结论发热伴咳嗽咳痰患儿应用痰热清注射液治疗的效果较好,可缩短其临床症状缓解时间,降低体内炎症因子水平,改善患儿发热、咳嗽的症状。Objective To investigate the clinical effect of Tanreqing Injection in treatment of fever children with cough and expectoration.Methods A total of 120 fever children with cough and expectoration admitted in our hospital from June 2018 to December 2019 were selected as research subjects and divided into control group and experimental group according to random number table method,with 60 cases in each group.The control group was treated with routine antiviral drugs,and the experimental group was treated with routine antiviral drugs and Tanreqing Injection.The clinical efficacy,relief time of expectoration,relief time of cough,recovery time of temperature,C-reactive protein(CRP),white blood cell count(WBC)and neutrophil ratio were compared between the two groups.Results The total effective rate of experimental group was higher than that of control group,and the difference was statistically significant(P<0.05).The relief time of expectoration,relief time of cough and recovery time of temperature in experimental group were shorter than those in control group,and the differences were statistically significant(P<0.05).The levels of CRP,WBC and neutrophil ratio in two groups after treatment were lower than those before treatment,and the differences were statistically significant(P<0.05).The levels of CRP,WBC and neutrophil ratio in experimental group after treatment were lower than those in control group,and the differences were statistically significant(P<0.05).Conclusion Tanreqing Injection in treatment of fever children with cough and expectoration has good effects,it can shorten relief time of clinical symptoms,decrease the levels of inflammatory factors,relieve the symptoms of fever and cough.

关 键 词：发热伴咳嗽咳痰 痰热清注射液 炎症因子水平 症状缓解 

分 类 号：R725.6[医药卫生—儿科]