有机磷中毒患者行血液灌流治疗配合急救护理对其临床转归指标及全血胆碱酯酶活力的影响  

Clinical study on hemoperfusion treatment of organophosphorus poisoning combined with emergency care for its clinical outcomes,AchE value and whole blood cholinesterase activity

作　　者：卢亚静 LU Yajing(Emergency Department of Luoyang Central Hospital,Luoyang 471000,China)

机构地区：[1]洛阳市中心医院急诊科,河南洛阳471000

出　　处：《包头医学院学报》2020年第7期69-73,共5页Journal of Baotou Medical College

摘　　要：目的:观察对机磷中毒患者行血液灌流治疗期间实施急救护理对其临床转归指标及全血胆碱酯酶活力的影响。方法:选取我院2018年6月至019年12月收治的63例有机磷中毒患者为本次研究对象,按随机数字表法分为观察组(n=33)与对照组(n=30)。两组患者入院后均行血液灌流治疗,对照组给予常规护理,观察组在行急救护理,观察两组患者临床转归指标及全血胆碱酯酶活力(AchE)变化的情况。结果:护理前,两组患者AchE比较无显著差异(P>0.05);护理后两组患者AchE有所上升,而观察组AchE显著高于对照组,两组差异具有统计学意义(P<0.01);观察组经急救护理后,AchE恢复至正常值70%以上的时间、临床症状缓解时间及住院时间均显著短于对照组(P<0.01);观察组抢救成功率(93.94%)显著高于对照组(73.33%)(P<0.05);观察组护理总满意率(93.94%)显著优于对照组(76.67%)(P<0.05)。结论:对有机磷中毒患行血液灌流治疗期间配合急救护理措施,能有提高临床抢救成功率,降低死亡率,促进临床转归,提高患者AchE值,并能提高患者护理满意度,在有机磷中毒患者临床抢救中起着至关重要的作用。Objective:To observe the effect of emergency nursing on clinical outcome index,AchE value and whole blood cholinesterase activity in patients with organic phosphorus poisoning during hemoperfusion treatment.Methods:Sixty-three patients with organophosphorus poisoning who were treated in our hospital from June 2018 to December 2019 were selected as the research object.They were divided into observation group(n=33)and control group(n=30)according to the random number table method.Patients in both groups were treated with hemoperfusion after admission.The control group was given routine care and the observation group was given emergency care.The clinical outcomes,AchE values,and changes in whole blood cholinesterase activity were observed in the two groups.Results:Before the nursing,there was no significant difference in the whole blood cholinesterase and AchE values between the two groups of patients(P>0.05).After the care,the whole blood cholinesterase and AchE values of the two groups of patients increased.Serum cholinesterase and AchE values were significantly higher than those in the control group,and the differences between the two groups were statistically significant(P<0.01).After the emergency treatment in the observation group,the time for AchE to return to more than 70%of the normal value,the time for clinical symptom relief,and the length of hospital stay were significantly shorter than those of the control group(P<0.01);the rescue success rate of the observation group(93.94%)was significantly higher than that of the control group(73.33%)(P<0.05);the overall satisfaction rate of the observation group(93.94%)was significantly better in the control group(76.67%)(P<0.05).Conclusion:The combination of first aid nursing measures during hemoperfusion treatment for patients with organophosphate poisoning can improve the success rate of clinical rescue,reduce the menstrual period,promote clinical outcomes,increase patients'whole blood cholinesterase and AchE values,and improve patient care.Satisfaction plays a v

关 键 词：血液灌流 有机磷中毒 急救护理 全血胆碱酯酶活力 

分 类 号：R473.5[医药卫生—护理学]