南京地区低能量骨折老年患者存在维生素D缺乏的回顾性研究  

Vitamin D deficiency in elderly patients with distal radius fractures and hip fractures in Nanjing area:A retrospective study

作　　者：叶蕾 王银河[2] 秦梅 YE Lei;WANG Yinhe;QIN Mei(Department of Clinical Pharmacy,the First Affiliated Hospital of Shandong First Medical University,Jinan 250014,China;Department of Orthopedic,the Affiliated Drum Tower Hospital of Nanjing University Medical School,Nanjing 210008,China;Department of Nursing,the First Affiliated Hospital of Shandong First Medical University,Jinan 250014,China)

机构地区：[1]山东第一医科大学第一附属医院临床药学,山东济南250014 [2]南京大学医学院附属鼓楼医院骨科,江苏南京210008 [3]山东第一医科大学第一附属医院护理学科,山东济南250014

出　　处：《中国骨质疏松杂志》2020年第9期1348-1351,共4页Chinese Journal of Osteoporosis

基　　金：国家自然科学基金(甲状旁腺素相关肽在促进骨折愈合中的作用和机制研究)(81271997)。

摘　　要：目的研究评估南京地区老年低能量骨折(桡骨远端和髋部骨折)患者维生素D[Vitamin D,Vit D;25(OH)D]水平,以及补充活性Vitamin D是否可以有效提高血清25(OH)D水平。方法回顾性研究南京鼓楼医院骨折联络服务(FLS)病例中90名老年(≥65岁)患者,桡骨远端骨折49名,髋部骨折41名,受伤后均给予口服活性Vitamin D治疗。分析受伤时和伤后4周的25(OH)D水平。结果所有桡骨远端骨折的患者,受伤时血清25(OH)D水平为14.83 ng/mL,伤后4周为21.23 ng/mL;在髋部骨折患者受伤时血清25(OH)D水平为9.92 ng/mL,伤后4周为18.96 ng/mL。结论桡骨远端以及髋部骨折老年患者的25(OH)D水平较低,有可能使肌肉力量下降导致跌倒风险增加,Vitamin D的补充可以有效提高血清25(OH)D水平。Objective To evaluate the vitamin D(Vit D,25(OH)D)levels in elderly patients with low energy fractures of the distal radius or hip fractures in Nanjing,and the effect vitamin D supplementation on serum 25(OH)D level.Methods A retrospective study of 90 elderly(≥65 years old)patients with fracture liaison service(FLS)in Nanjing Drum Tower Hospital,including 49 distal radius fractures and 41 hip fractures was conducted.The patients received oral vitamin D after injury.Serum 25(OH)D levels were analyzed at the time of injury,and 4 weeks after the injury.Results In all patients with distal radius fractures(n=49),serum 25(OH)D level was 14.83 ng/mL at the time of injury and 21.23 ng/mL at 4 weeks after injury,respectively.Serum 25(OH)D levels were 9.92 ng/mL at the time of injury in hip fracture patients(N=49)and 18.96 ng/mL at 4 weeks after injury.Conclusion Vitamin D levels were lower in elderly patients with distal radius or hip fractures.Low vitamin D levels may decrease muscle strength and increase the risk of falls.Vitamin D supplementation can effectively increase serum 25(OH)D levels.

关 键 词：低能量骨折 桡骨远端骨折 髋部骨折 维生素D 南京 

分 类 号：R683.4[医药卫生—骨科学]