基于“正虚致痹”理论探讨“久病入络”与骨质疏松症的相关性机理  

The mechanism of the correlation between long illness into the collaterals theory and osteoporosis based on the theory of numbness caused by deficiency

作　　者：史恒蔚 李红专[2] 马同 李非[2] 薛旭 李百通 张敏[1] SHI Hengwei;LI Hongzhuan;MA Tong;LI Fei;XUE Xu;LI Baitong;ZHANG Min(Gansu university of Traditional Chinese Medicine,Lanzhou 730030,China;Gansu Provincial Hospital of Traditional Chinese Medicine,Lanzhou 730050,China)

机构地区：[1]甘肃中医药大学,甘肃兰州730030 [2]甘肃省中医院,甘肃兰州730050

出　　处：《中国骨质疏松杂志》2020年第9期1395-1398,共4页Chinese Journal of Osteoporosis

基　　金：国家自然科学基金(81760877);卫生部医药卫生科技发展研究中心科研基金(W2014ZT210);甘肃省卫生行业项目(GWGL2014-11);兰州市创新人才项目(2018-RC-99);甘肃省自然科学基(17JR5RA054);甘肃中医药大学研究生创新基金项目(CX2018-10)。

摘　　要：骨质疏松症(osteoporosis,OP)是当今世界最常见的代谢性骨病之一,严重影响着中老年患者的健康及生活质量。"正虚致痹"、"久病入络"均是祖国医学中疾病防治的重要指导思想之一。"正虚致痹"指人体正气耗损失于固护,阳气亏虚难御外邪,日久风寒湿邪乘虚而入,发为痹症;"久病入络"以虚、瘀立论,该理论亦被广泛应用于OP的中医药辩证施治,取得了良好的临床疗效。两种理论与部分现代医学相关研究相互印证,有力阐述了"久病入络-正虚致痹-骨质疏松症"间存在密切相关性,病久入络,迁延不愈,耗气伤血,终成"正虚"之象,最终可能导致OP(痹症)的发生发展,是故三者之间在病理上可互为因果。本文作者通过查阅大量国内外文献,从中医"正虚致痹"理论出发,对"久病入络-正虚致痹-骨质疏松症"相关性机理做一探讨,旨在总结中医"正虚致痹"与"久病入络"理论在OP防治过程中的重要指导作用,以期对OP防治提供新思路。Osteoporosis(OP)is one of the most common metabolic bone diseases in the world.It seriously affects the health and quality of life of the middle-aged and elderly patients.Numbness caused by deficiency and long illness into the collaterals theory are the important guiding principles in the prevention and treatment of diseases in Chinese medicine.Numbness caused by deficiency refers to the loss of the body's positive qi consumption in the solid protection.Deficiency of Yang qi is unable to ward off foreign evil.As the wind and cold and dampness exist over time,arthralgia syndrome may occur.The theory of long illness into collaterals is based on deficiency and stasis,which has been widely applied to the dialectical treatment of traditional Chinese medicine in OP and has achieved good clinical effect.The two theories are related to part of the modern medical research to confirm each other,and powerfully expound the close relationship of long illness into collaterals-numbness caused by deficiency-osteoporosis.Long time illness may enter the collaterals,delay the healing,consume gas and blood,leading to virtual image and eventually to the development of OP(poliomyelitis).Therefore,the pathology of the three is as causes and consequences.In this paper,the authors explore the pathogenesis of long illness into collaterals-numbness caused by deficiency-osteoporosis base on traditional Chinese medicine numbness caused by deficiency theory through large literature screening,aiming to summarize the important guiding role of long illness into collaterals-numbness caused by deficiency theory in the prevention and treatment of the OP process,in order to provide new ideas for prevention and treatment of the OP.

关 键 词：正虚致痹 久病入络 骨质疏松症 相关性机理 

分 类 号：R255.6[医药卫生—中医内科学]