高心率下低剂量128层双源CT前门控冠脉造影:初步探究  

Low Dose 128-slice Dual Source CT Prospective ECG Gated Coronary Angiography with High Heart Rates: Initial inquiry

作　　者：宋利华 张迪 任向宇 孙晓琳 殷兆丽 包丽丽 包丽薇[2] Song Lihua;Zhang Di;Ren Xiangyu;Sun Xiaolin;Yin Zhaoli;Bao Lili;Bao Liwei(Basic medical college of Inner Mongolia Medical University,Hohhot,010059;The Affiliated Hospital of Inner Mongolia Medical University,Hohhot,010050)

机构地区：[1]内蒙古医科大学基础医学院,呼和浩特010059 [2]内蒙古医科大学附属医院,呼和浩特010050

出　　处：《基因组学与应用生物学》2020年第7期3213-3218,共6页Genomics and Applied Biology

基　　金：内蒙古自然科学基金(2015MS0888);内蒙古自治区高等学校科学研究项目(MJZY13425)共同资助。

摘　　要：本研究拟通过低剂量联合措施对高心率病人进行双低CT冠状动脉造影,评价新技术可行性。本研究入组病人39例,随机分为A、B两组。A组20例采用前门控低剂量联合措施,B组19例采用前门控常规模式扫描。比较辐射剂量与碘负荷;比较主观图像质量与客观图像质量;评价A、B两组管腔测量可重复性。结果显示A组病人有效剂量为(0.92±0.27)mSv,B组病人有效剂量为(1.95±0.78)m Sv,t=-5.567,p<0.01。A组病人对比剂容积为(42.00±6.16)mL,B组病人对比剂容积(54.32±6.16)m L,t=-6.245,p<0.01。冠状动脉节段A组(n=231)评分(3.48±0.66)分,B组(n=244)评分(3.59±0.57)分,t=-1.848,p=0.065,差异无统计学意义。A组CNR为(18.84±4.62),B组为(21.21±2.53),t=-1.974,p=0.056,差异无统计学意义。A组组间差值为(0.04±0.33)mm,B组组间差值为(-0.18±0.43)mm,t=1.857,p=0.071,差异无统计学意义。通过低剂量联合措施优化可以使得前瞻性心电门控序列CTCA扫描最大限度降低辐射剂量与对比剂用量,而图像质量无变化。The purpose of this study was to evaluate the feasibility of clinical application for ultra-low radiation dose and contrast agent in CT coronary angiography in patients with high heart rate.The results showed that 39 patients were randomly divided into group A and group B.In group A,20 patients underwent PGA combining with low dose methods,while the group B(n=19)was treated with routine PGA.The subjective image quality and objective image quality were compared by readers for two groups.The luminal repeatability for two groups was evaluated.Results The ED in group A was(0.92±0.27)mSv,and(1.95±0.78)mSv in group B,the difference was statistically significant(t=-5.567,p<0.01).The contrast agent in group A was(42.00±6.16)m L,and was(54.32±6.16)mL in group B,t=-6.245,p<0.01.Coronary artery segment score in group A(n=231)was(3.48±0.66),and(3.59±0.57)in group B(n=244),t=-1.848,p=0.065,the difference was not statistically significant.CNR in group A was(18.84±4.62),there was(21.21±2.53)in group B,t=-1.974,p=0.056,the difference was not statistically significant.The measure difference in group A was(0.04±0.33)mm,it was(-0.18±0.43)mm in group B,t=1.857,p=0.071,the difference was not statistically significant.Combining with methods of reducing dose,PGA-CTCA could maximize reducing radiation dose and contrast agent,and it was worth study for clinical application.

关 键 词：双源CT 冠脉造影 图像质量 辐射剂量 对比剂剂量 

分 类 号：R816.2[医药卫生—放射医学]