Clinical evaluation of cochlear implantation in children younger than 12 months of age  

作　　者：Yang Yang Min Chen Jun Zheng Jinsheng Hao Bing Liu Wei Liu Bei Li Jianbo Shao Haihong Liu Xin Ni Jie Zhang 

机构地区：[1]Department of Otorhinolaryngology Head and Neck Surgery,Beijing Children’s Hospital,Capital Medical University,National Center for Children’s Health,Beijing,China [2]Beijing Tongren Hospital,Capital Medical University,Beijing,China [3]Beijing Key Laboratory for Pediatric Diseases of Otolaryngology‐Head and Neck Surgery,Beijing,China

出　　处：《Pediatric Investigation》2020年第2期99-103,共5页儿科学研究（英文）

基　　金：Special Fund of The Pediatric Medical Coordinated Development Center of Beijing Hospitals Authority(No.XTYB201828);the Capital Health Research and Development of Special Project(2016-1-5014)。

摘　　要：Importance Cochlear implantation(CI)is an effective therapy for patients with severe to profound sensorineural hearing loss.It remains controversial whether children younger than 12 months of age should undergo CI.Objective To evaluate the safety and effectiveness of CI in children younger than 12 months of age.Methods We performed a retrospective study of clinical data of pediatric patients younger than 12 months of age who underwent CI and were followed up for 1 to 2 years.Patients’developmental levels were evaluated by the Gesell score before CI.Intraoperative and postoperative complications were recorded to evaluate the safety of CI.Auditory and speech abilities were scored by the LittlEARS®auditory questionnaire(LEAQ),categories of auditory performance(CAP),speech intelligibility rating(SIR),infant‐toddler meaningful auditory integration scale(IT‐MAIS),and meaningful use of speech scale(MUSS)at 1,2,3,6,9,and 12 months after CI.The associations between clinical characteristics before CI and postoperative scores at 1 year after CI were analyzed by the linear mixed‐effects model.Results Eighty‐nine children(47 boys and 42 girls)were included in this study(mean age at CI,9.2±1.6 months).Sixteen patients were diagnosed with cochlear malformation and 16 underwent bilateral CI.No severe complications occurred in any patients.The mean developmental quotient of the Gesell score was 78.00±10.03.The median LEAQ scores were 0,5,10,16,22,26 and 30 before and at 1,2,3,6,9,and 12 months after CI,respectively.These findings implied that the LEAQ score greatly improved in the first year after CI.The overall CAP,SIR,IT‐MAIS,and MUSS scores also increased with increasing duration after CI.No significant associations were detected between clinical characteristics(age,sex,implant number,pre‐CI Gesell score,and inner ear malformation)and LEAQ outcomes at 12 months after CI.Interpretation With increasing duration after CI,auditory and speech behavior dramatically improve in young children.Our findings indicate tha

关 键 词：Cochlear implantation Age CHILDREN OUTCOME 

分 类 号：R764.9[医药卫生—耳鼻咽喉科]