局灶性机化性肺炎及周围型肺癌能谱CT表现  

Spectral CT findings of focal organizing pneumonia and peripheral lung cancer

作　　者：张国晋[1] 曹云太 张婧[1] 赵志勇[1] 张文娟[1] 黄乐乐[1] 周俊林[1,2] ZHANG Guojin;CAO Yuntai;ZHANG Jing;ZHAO Zhiyong;ZHANG Wenjuan;HUANG Lele;ZHOU Junlin(Department of Radiology,Lanzhou University Second Hospital,Lanzhou University Second Clinical School of Medicine,Lanzhou 730030,China;Key Laboratory of Medical Imaging of Gansu Province,Lanzhou 730030,China)

机构地区：[1]兰州大学第二医院放射科兰州大学第二临床医学院,甘肃兰州730030 [2]甘肃省医学影像重点实验室,甘肃兰州730030

出　　处：《中国医学影像技术》2020年第9期1330-1334,共5页Chinese Journal of Medical Imaging Technology

基　　金：甘肃省医学影像重点实验室开放基金项目(GSYX202010);兰州市人才创新创业项目(2016-RC-58)。

摘　　要：目的观察局灶性机化性肺炎(FOP)和周围型肺癌(PLC)的能谱CT表现。方法回顾性分析40例经病理证实的FOP(FOP组)和60例PLC患者(PLC组),均接受胸部双期能谱CT检查。测量并记录病灶动脉期及静脉期单能量图像CT 40~100 keV值(HU)、碘(水)值、水(碘)值及有效原子序数,绘制相应能谱曲线,计算能谱曲线斜率(λHU);比较2组各定量参数的差异。结果2组患者年龄、性别、临床症状、病灶大小及位置差异均无统计学意义(P均>0.05)。PLC组动脉期CT 40 keV、CT 50 keV、CT 60 keV及CT 70 keV值、λ70 keV、碘(水)值、有效原子序数均高于FOP组(t=3.46、3.08、3.08、2.03、2.32、2.69、2.73,P均<0.05);静脉期CT 40 keV、CT 50 keV、CT 60 keV及CT 70 keV值、λ70 keV、碘(水)值、有效原子序数均低于FOP组(t=-3.51、-3.82、-3.01、-2.30、-2.76、-2.40、-2.43,P均<0.05);其余动脉期及静脉期能谱参数值组间差异均无统计学意义(P均>0.05)。结论FOP与PLC能谱CT表现存在一定差异,可为鉴别诊断提供参考。Objective To observe the energy spectral CT manifestations of focal organizing pneumonia(FOP)and peripheral lung cancer(PLC).Methods Data of 40 patients with FOP(FOP group)and 60 patients with PLC(PLC group)confirmed by pathology who underwent chest dual-phase energy spectral CT were retrospectively analyzed.CT 40~100 keV values on single energy images,iodine concentration,water concentration and effective atomic number at arterial and venous phase of lesions were measured and recorded,respectively.The corresponding energy spectral curve was drawn,and the slope of the curve was calculated.The quantitative parameters were compared between 2 groups.Results There was no statistically differences of patients'age,gender,clinical symptoms nor lesions'size or location between 2 groups(all P>0.05).CT 40 keV,CT 50 keV,CT 60 keV and CT 70 keV values,λ70 keV,iodine concentration,effective atomic number at arterial phase in PLC group were all higher than those in FOP group(t=3.46,3.08,3.08,2.03,2.32,2.69,2.73,all P<0.05),while at venous phase in PLC group were all lower than those in FOP group(t=-3.51,-3.82,-3.01,-2.30,-2.76,-2.40,-2.43,all P<0.05).No statistical difference of other energy spectrum parameters at arterial phase or venous phase was found between 2 groups(all P>0.05).Conclusion Energy spectral CT findings of FOP and PLC had certain difference,providing references for differential diagnosis of FOP and PLC.

关 键 词：肺肿瘤 肺炎 诊断 鉴别 体层摄影术 X线计算机 能谱成像 

分 类 号：R563[医药卫生—呼吸系统] R814.42[医药卫生—内科学]