奥曲肽治疗肝硬化合并上消化道出血的临床疗效  

Clinical Effect of Octreotide in the Treatment of Cirrhosis with Upper Gastrointestinal Hemorrhage

作　　者：李雁滨 LI Yanbin(Department of Emergency,the Central Hospital of Yingkou Economic and Technological Development Zone(The Sixth People's Hospital of Yingkou),Yingkou 115007,China)

机构地区：[1]辽宁省营口经济技术开发区中心医院急诊科(营口市第六人民医院),辽宁营口115007

出　　处：《中国医药指南》2020年第26期35-36,共2页Guide of China Medicine

摘　　要：目的探究奥曲肽治疗肝硬化合并上消化道出血的临床疗效。方法研究对象为98例肝硬化合并上消化道出血患者,分为两组,49例给予常规治疗作为对照组,49例给予奥曲肽治疗作为试验组,对比两组治疗有效率、不良反应率、平均止血时间及出血复发率。结果试验组的治疗总有效率明显高于对照组,不良反应率、出血复发率、止血时间均明显少于对照组(均P<0.05),差异存在统计学意义。结论在肝硬化合并上消化道出血患者中给予奥曲肽药物治疗,其治疗效果显著,不良反应少,出血复发率低,能够显著改善患者症状,促使其生活质量的提高,在临床上的应用价值较高。Objective To explore the clinical effi cacy of octreotide in the treatment of cirrhosis with upper gastrointestinal bleeding.Methods The subjects of the study were 98 patients with cirrhosis complicated by upper gastrointestinal bleeding,divided into two groups:49 patients who received conventional treatment as the control group,and 49 patients who received octreotide as the experimental group.The effi cacy,adverse reaction rate,bleeding recurrence rate and hemostasis time of the two groups were compared.Results The total eff ective rate of treatment in the experimental group was signifi cantly higher than that in the control group.The adverse reaction rate,bleeding recurrence rate,and hemostasis time in the experimental group were signifi cantly less than those in the control group(all P<0.05),and the diff erence was statistically signifi cant.Conclusion Octreotide drug therapy in patients with cirrhosis complicated by upper gastrointestinal hemorrhage has signifi cant therapeutic eff ect,few adverse reactions and low recurrence rate of hemorrhage,which can signifi cantly improve patients'symptoms and promote the improvement of their quality of life,and has high clinical application value.

关 键 词：肝硬化 上消化道出血 奥曲肽 临床疗效 

分 类 号：R657.31[医药卫生—外科学] R573.2[医药卫生—临床医学]